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EPHB2 — IFI27
Text-mined interactions from Literome
Wolf et al., Diabetologia 2003
(Hypertrophy) :
Activation of
Erk 1,2
leads to phosphorylation of
p27 ( Kip1 ) in vitro and in vivo
Khan et al., J Lipid Res 2006
(Mammary Neoplasms, Animal...) :
Indeed, inhibition of
ERK1/ERK2 phosphorylation by DHA, U0126 [ chemical MAPK extracellularly signal regulated kinase kinase ( MEK ) inhibitor ], and MEK ( SA ) ( cells expressing dominant negative constructs of MEK )
resulted in the accumulation of
p27 ( Kip1 )
Yin et al., Biol Pharm Bull 2007
:
OR-heparin also inhibited high glucose activated
ERK1/2 phosphorylation,
induced p27 ( Kip1 ) expression, and suppressed reactive oxygen species ( ROS ) accumulation in a dose dependent manner
Lee et al., Invest Ophthalmol Vis Sci 2011
:
ERK1/2 was also
involved in FGF-2 stimulated CEC proliferation and phosphorylation of
p27 at Ser10 and Thr187 in parallel to phosphatidylinositol (PI) 3-kinase