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IFNB1 — IL1B

Text-mined interactions from Literome

Peters et al., Immunology 2003 : Mitogen stimulation of embryonic day 18 and day 1 post-hatch thymocytes induced up-regulation of IFN-gamma, IL-1beta and TGF-beta transcripts, and down-regulation of IFN-alpha, IFN-beta and IL-2 transcripts, with a higher induction of IFN-gamma, IL-1beta and TGF-beta transcripts in more immature T-cell-receptor negative ( TCR- ) than TCR+ ( TCR1+, TCR2+, or TCR3+ ) subsets
Molnarfi et al., J Neuroimmunol 2004 : Furthermore, we recently demonstrated that IFNbeta inhibits the production of IL-1beta and tumor necrosis factor-alpha (TNF) in human monocytes activated by cellular contact with stimulated T cells, a mechanism which we suspected of playing an important part in the pathogenesis of chronic inflammatory diseases including MS ... Here we compare modulatory effects of IFNbeta on the production of proinflammatory cytokines ( IL-1beta , IL-1alpha, TNF, and IL-6 ) and IL-1Ra in human monocytes stimulated by lipopolysaccharides (LPS) and isolated plasma membranes of stimulated T cells ( msHUT ), which are likely to reflect monocyte activation in acute and chronic inflammation, respectively ... IFNbeta inhibited the expression ( mRNA ) and production ( protein ) of IL-1beta and TNF, while enhancing those of IL-1Ra in monocytes activated by msHUT
Zang et al., Mult Scler 2004 (Multiple Sclerosis, Chronic Progressive...) : The results revealed that IFN beta inhibited intracellular production of interleukin (IL)-1b ( P < 0.01 ) in both monocytes exposed to in vitro treatment of IFN beta and monocytes analysed ex vivo from MS patients treated with IFN beta
Tsung et al., Am J Physiol Gastrointest Liver Physiol 2006 (Reperfusion Injury) : Whereas IFN-gamma and IFN-beta were strong inducers of IRF-1 mRNA ( > 10-fold ) in a time- and dose dependent manner, TNF-alpha and IL-1beta also induced IRF-1 mRNA to a lesser extent ( 2- to 3-fold )
Jin et al., Brain Res 2007 : Although IFN-beta enhanced the production of tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta , and nitric oxide ( NO ) by activated microglia, these molecules did not directly induce neurotoxicity in cultured cortical neurons
Zhang et al., J Immunol 2009 (Multiple Sclerosis, Relapsing-Remitting) : TLR7 expression was also necessary for the IFN-beta1a induced inhibition of IL-1beta and IL-23 and the induction of IL-27 secretion by DCs
Zhang et al., Clin Neurol Neurosurg 2010 (Autoimmune Diseases...) : IFNbeta inhibited IL-1beta , IL-23 and transforming growth factor ( TGF ) -beta ( which induce Th17 cell differentiation ), and induced IL-27, IL-12p35 and IL-10 ( which suppress it ) in dendritic cells (DCs) and B-cells
Coclet-Ninin et al., Eur Cytokine Netw 1997 : Interferon-beta not only inhibits interleukin-1beta and tumor necrosis factor-alpha but stimulates interleukin-1 receptor antagonist production in human peripheral blood mononuclear cells
Singh et al., Cancer Res 1998 (Melanoma) : However, IFN-alpha and IFN-beta inhibited IL-1beta or TNF-alpha mediated up-regulation of IL-8 mRNA