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APIP — CASP1
Text-mined interactions from Literome
Cho et al., J Biol Chem 2004
(Anoxia...) :
Exogenous
APIP inhibits cytochrome c-induced activation of
caspase-3 and caspase-9, and suppresses cell death triggered by mitochondrial apoptotic stimuli through inhibiting the downstream activity of cytochrome c released from mitochondria
Cho et al., Oncogene 2007
(Anoxia) :
Unlike etoposide, however,
APIP induces the sustained activation of AKT and ERK1/2 and the phosphorylation of
caspase-9 during hypoxia