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IKBKE — IRF8

Text-mined interactions from Literome

Schröder et al., EMBO J 2008 : Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon mediated IRF activation ... Here, we describe a novel VACV protein, K7, which can inhibit PRR induced IFN-beta induction by preventing TBK1/IKKepsilon mediated IRF activation ... Therefore, this study shows for the first time the involvement of a DEAD box helicase in TBK1/IKKepsilon mediated IRF activation and Ifnb promoter induction
Balkhi et al., Cell Signal 2010 (Inflammation) : In infected cells, IRF-3 and IRF-7 are activated by TBK-1 and IKK epsilon mediated phosphorylation, while the kinase, phosphorylating IRF-5 in the MyD88 signalling pathway has not yet been identified