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IRF1 — MAPK15
Text-mined interactions from Literome
Lee et al., Cancer Res 2005
(MAP Kinase Signaling System) :
We found that IL-1beta regulated IRF-1 gene expression through stimulation of p38
mitogen activated protein kinase ( MAPK ), which mediated signal transducer and activator of transcription 1 ( Stat1 ) serine phosphorylation and Stat1 nuclear translocation to
activate the
IRF-1 promoter
Kanda et al., Endocrinology 2007
(MAP Kinase Signaling System...) :
Inhibitors of Janus kinase ( JAK ), p38
MAPK , and MAPK/ERK kinase (MEK)
suppressed prolactin- plus IFN-gamma induced CXCL9, CXCL10, and CXCL11 production and NF-kappaB, STAT1, and
IRF-1 activities
Kanda et al., Eur J Immunol 2007
:
Inhibitors of PI3 K, p38
MAPK , and MEK
suppressed IL-18 plus IFN-gamma induced CXCL9, CXCL10, and CXCL11 production and NF-kappaB, STAT1, and
IRF-1 activities
Hickey et al., J Leukoc Biol 2008
:
Our findings demonstrate that CyaA modulates TLR agonist induced IL-10 and IL-12p70 production in DC by, respectively, enhancing
MAPK phosphorylation and
inhibiting IRF-1 and IRF-8 expression and that this is mediated by elevation of intercellular cAMP concentrations
Shen et al., Leukemia & lymphoma 2011
(Leukemia, Monocytic, Acute...) :
RA induces
MAPK dependent expression of
IRF-1 ...
Interferon regulatory factor-1 binds c-Cbl,
enhances mitogen activated protein kinase signaling and promotes retinoic acid induced differentiation of HL-60 human myelo-monoblastic leukemia cells