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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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CA2 — DDT

Text-mined interactions from Literome

Wärngård et al., Chem Biol Interact 1988 : As the effects of calcium are closely associated with the multifunctional protein calmodulin (CaM) in most cells the potential binding of DDT to CaM and subsequent effects on CaM stimulated Ca2+/Mg2+-ATPase activity were studied ... DDT inhibited CaM stimulated Ca2+/Mg2+-ATPase activity and bound to CaM in a manner similar to established CaM-inhibitors
Mourelle et al., J Appl Toxicol 1985 : DDT , but not toxaphene, also led to a decrease in Mg2+-ATPase ( 20 % ) and Ca2+-ATPase ( 35 % ) activity
Yamaguchi et al., Biochem Pharmacol 1993 : The sulfhydryl group reducing agent dithiothreitol ( DTT ) protected the nuclei from the effects of heavy metals ; DDT ( 1 mM ) almost completely blocked Zn ( 2+ ) - or Cu ( 2+ ) -induced Ca2+ release and inhibition of Ca2+ uptake