◀ Back to WNT16

PITX2 — WNT16

Text-mined interactions from Literome

Abu-Elmagd et al., Dev Biol 2010 : In addition, we show that Pitx2 expression is regulated by canonical Wnt signaling in the epaxial somite and second branchial arch, but not in the limb or the first branchial arch
Hasegawa et al., Acta histochemica et cytochemica 2010 : These results suggest that the enhancement of Pitx-2 expression induced by activated Wnt signaling leads to delays in ureteric bud branching and subsequent renal agenesis
Freisinger et al., PLoS Genet 2010 (Calcium Signaling) : Regulator of G protein Signaling (RGS) proteins can accelerate inactivation of G proteins by acting as G protein GTPase activating proteins ( GAPs ), however, the possible role of RGS proteins in non-canonical Wnt signaling and development is not known
Zacharias et al., Dev Dyn 2010 : Canonical Wnt/ß-catenin signaling is required for maintenance but not activation of Pitx2 expression in neural crest during eye development ... We use neural crest-specific ablation of Ctnnb1 to demonstrate that canonical Wnt signaling is not required for initial activation of Pitx2 in neural crest ... LEF-1 and ß-catenin bind Pitx2 promoter sequences in ocular neural crest, indicating a likely direct effect of canonical Wnt signaling on Pitx2 expression
Shi et al., J Biol Chem 2012 : Here we show that Wnt signaling enhances the expression of another RGS domain containing protein, PDZ-RGS3
Schneider et al., PloS one 2012 : This study was performed to test the hypothesis that Axin RGS-Gna interactions would be required to attenuate Wnt signaling
Li et al., PloS one 2013 (Wnt Signaling Pathway) : A Topflash reporter system was employed showing PITX2 activation of Wnt signaling, which is attenuated by Dact2