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IL12A — TCF7

Text-mined interactions from Literome

Pardoux et al., Blood 1999 : In addition, TGF-beta was found to significantly inhibit IL-12 induced phosphorylation of the STAT4 transcription factor
Wang et al., J Immunol 2000 : An IFN-gamma-inducible transcription factor , IFN consensus sequence binding protein ( ICSBP ), stimulates IL-12 p40 expression in macrophages
Matikainen et al., Eur J Immunol 2001 : We show that Stat4 activation is transient in cells stimulated with IFN-alpha, whereas IL-12 induces more long lasting activation of the transcription factor
Matasić et al., Croat Med J 2001 : We quantified the effect of drugs on the dendritic cell characteristics, such as stimulation of autologous and allogeneic pan-T cell proliferation, surface marker phenotype, IL-12 p40 subunit secretion, and activation of nuclear transcription factor ( NF)-kappa B
Rahim et al., Immunology 2005 : Interleukin-10 (IL-10) mediated suppression of IL-12 production in RAW 264.7 cells also involves c-rel transcription factor ... We demonstrate that the c-rel transcription factor also plays a major role in IL-10 mediated IL-12 suppression
Saraiva et al., Immunity 2009 : We showed that development of IL-10 producing Th1 cells required high T cell receptor ( TCR ) ligation, sustained ERK1 and ERK2 MAP kinases phosphorylation, and IL-12 induced STAT4 transcription factor activation
Lupov et al., Blood 2011 (Lymphoma...) : Signal Transducer and Activator of Transcription 4 ( STAT4 ) is a transcription factor that is activated by IL-12 signaling and promotes Th1-cell differentiation and IFN-? production