Zhou et al., American journal of physiology. Renal physiology 2006
(Acute Kidney Injury) :
The purpose of this study was to evaluate whether upregulated p21 , a cell cycle-inhibitory protein, contributes to cisplatin ( CDDP ) -induced acute renal failure ( ARF ) and to acquired resistance to rechallenge injury with CDDP in rats
Burd et al., PLoS Genet 2010
(Atherosclerosis) :
These results identify novel circular RNA products emanating from the ANRIL locus and suggest causal variants at 9p21.3 regulate INK4/ARF expression and ASVD risk by modulating ANRIL expression and/or structure
Chen et al., J Biol Chem 2012
(Lymphoma, B-Cell) :
p14(ARF) also attenuated TGF-ß1 induced p21 ( Cip1/WAF1 ) induction, which was reversible by p53 siRNA, indicating the involvement of mutant p53 in controlling the TGF-ß1 induced expression of p21 ( Cip1/WAF1 )