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PTX3 — TLR10

Text-mined interactions from Literome

Garlanda et al., Annu Rev Immunol 2005 (Inflammation...) : PTX3 is produced by a variety of cells and tissues, most notably dendritic cells and macrophages, in response to Toll-like receptor ( TLR ) engagement and inflammatory cytokines
Doni et al., J Leukoc Biol 2006 : Dendritic cells ( DC ) of myelomonocytic origin, but not plasmacytoid DC, are a major source of PTX3 in response to Toll-like receptor ( TLR ) engagement ... PTX3 production was induced by TLR ligands, CD40 ligand, and interleukin (IL)-1beta and was suppressed by dexamethasone, 1alpha, 25-dihydroxivitamin D3, and prostaglandin E2
Mantovani et al., Vascul Pharmacol 2006 (Cardiovascular Diseases...) : CRP and SAP are produced primarily in the liver in response to IL-6, while PTX3 is produced by a variety of tissues and cells and in particular by innate immunity cells in response to proinflammatory signals and Toll-like receptor ( TLR ) engagement
Maina et al., J Leukoc Biol 2009 (Inflammation) : Divergent effects were observed with IL-10, which synergizes with TLR mediated PTX3 induction but inhibits LPS induced TSG-6 transcription
Deban et al., Biofactors 2009 (Inflammation) : PTX3 is produced by a variety of cells and tissues, most notably dendritic cells and macrophages, in response to Toll-like receptor ( TLR ) engagement and inflammatory cytokines
Garlanda et al., Curr Pharm Des 2011 (Atherosclerosis...) : CRP and SAP are produced primarily in the liver in response to IL-6, while PTX3 is produced by a variety of tissues and cells and in particular by innate immunity cells in response to proinflammatory signals and Toll-like receptor ( TLR ) engagement
Balhara et al., Frontiers in immunology 2013 : PTX3 is secreted by a diverse variety of cells, ranging from immune cells to structural cells, in response to Toll like receptor ( TLR ) engagement, inflammatory stimuli, and physical and chemical stress