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CASC3 — CSF2

Text-mined interactions from Literome

Jang et al., Arthritis Res Ther 2006 (Arthritis, Rheumatoid) : However, MLN51 knock-down by siRNA completely blocked the GM-CSF/SF mediated proliferation of RA FLSs. Taken together, our results imply that MLN51 , induced by GM-CSF , is important in the proliferation of RA FLSs in the pathogenesis of RA
Ha et al., FEBS J 2008 (Arthritis, Rheumatoid) : In this study, we have found that : ( 1 ) GM-CSF mediated MLN51 upregulation is attributable to both transcriptional and post-translational control in rheumatoid arthritis fibroblast-like synoviocytes ; ( 2 ) p38 mitogen activated protein kinase plays a key role in the upregulation of MLN51 ; and ( 3 ) FLICE-inhibitory protein is upregulated downstream of MLN51 in response to GM-CSF, resulting in the proliferation of fibroblast-like synoviocytes