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CASP4 — FGF2

Text-mined interactions from Literome

Slomiany et al., J Physiol Pharmacol 1998 (Chronic Disease...) : Role of basic fibroblast growth factor in the suppression of apoptotic caspase-3 during chronic gastric ulcer healing
Messmer et al., J Am Soc Nephrol 2000 : In mechanistic terms, bFGF synergistically increased TNF-alpha induced mitochondrial permeability transition, the release of cytochrome c from mitochondria to the cytosol, and upregulation of the proapoptotic protein Bak and significantly enhanced activation of caspase-8 protease activity
Zhou et al., Zhonghua Yan Ke Za Zhi 2003 : Visible light exposure over threshold causes upregulation of endogenous bFGF and FGFR1, downregulation of Bcl-2 and activation of caspase-3 in human RPE cells
Liu et al., Zhonghua Yi Xue Za Zhi 2005 (Spinal Cord Injuries) : bFGF inhibits the expression of caspase 3 protein, reduces the caspase 3 activity, lessens the secondary cell apoptosis in the injured spinal cord, and promotes nerve function recovery of spinal cord
Xiao et al., Acta Biochim Biophys Sin (Shanghai) 2008 (Carcinoma, Small Cell...) : FGF-2 reduced apoptosis induced by serum starvation and up-regulated survivin expression in H446 cells in a dose dependent and time dependent manner, and inhibited caspase-3 activity
Keller et al., J Immunol 2009 : Recently, we demonstrated that active caspase-1 , whose activation is dependent on inflammasome complexes, is required for unconventional protein secretion of proinflammatory cytokines such as IL-1 and of the proangiogenic fibroblast growth factor 2
Aras et al., Brain Res 2012 (Gliosis) : Broad spectrum caspase inhibition with zVAD significantly attenuated increases in glutamine synthetase and fibroblast growth factor-2 in the reactive astrocytes