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FOSL1 — PIK3CA

Text-mined interactions from Literome

Zhang et al., J Biol Chem 2006 : In this study we investigated a potential link between the PI3K-Akt pathway and the cigarette smoke ( CS ) -stimulated epidermal growth factor receptor mediated FRA-1 induction in non-oncogenic HBE cells ... We found that the PI3K through p21 activated kinase 1 regulates FRA-1 proto-oncogene induction by CS and the subsequent activation of the Elk1 and cAMP-response element binding protein transcription factors that are bound to the promoter in HBE cells
Ramos-Nino et al., Molecular cancer 2007 (Mesothelioma) : Cell lines with PI3K dependent Fra-1 expression were SV40 positive and expressed the lowest basal Fra-1 levels
Ramos-Nino et al., Mol Cancer Ther 2008 : The novel drug combination of ranpirnase and rosiglitazone is a promising combination to treat cancers with increased PI3K dependent Fra-1 expression or Survivin
Kent et al., Mol Cell Biol 2011 : Nuclear FOSL1 increased during trophoblast cell differentiation in a PI3K/AKT dependent manner