Gene interactions and pathways from curated databases and text-mining

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HMGA1 — RELA

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Baron et al., PloS one 2010 (Endotoxemia...) : Transfection studies demonstrated a critical role for HMGA1 in facilitating cytokine and NF-kappaB induction of P-selectin promoter activity, and Dist A inhibited binding of HMGA1 to this AT-rich region of the P-selectin promoter in vivo
Himes et al., Immunity 1996 : We further show that the high mobility group protein HMG I(Y) can bind to the CD28REs of both GM-CSF and IL-2 and that this binding is critical for c-Rel, but not RelA , binding
Klein-Hessling et al., Proc Natl Acad Sci U S A 1996 (Leukemia, T-Cell...) : It has been shown that HMG I(Y) proteins enhance NF-kappa B binding to the interferon beta promoter and virus mediated interferon beta promoter induction