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MAPK3 — VCAM1

Text-mined interactions from Literome

Jiang et al., J Biol Chem 2004 (Inflammation) : Angiotensin II differentially regulates interleukin-1-beta-inducible NO synthase (iNOS) and vascular cell adhesion molecule-1 ( VCAM-1 ) expression : role of p38 MAPK
Wang et al., Am J Physiol Lung Cell Mol Physiol 2005 : Together, these results suggest that in HTSMC, activation of p42/p44 MAPK , p38, JNK, and NF-kappaB pathways is essential for IL-1beta induced VCAM-1 gene expression ... Together, these results suggest that in HTSMC, activation of p42/p44 MAPK , p38, JNK, and NF-kappaB pathways is essential for IL-1beta induced VCAM-1 gene expression
Kawanami et al., Atherosclerosis 2006 (Atherosclerosis) : Taken together, our findings suggest that VCAM-1 induction by CRP is mediated by PKC, p38MAPK , tyrosine kinase and the NF-kappaB dependent signaling pathways in vascular endothelial cells
Kim et al., Cardiovasc Res 2006 : Furthermore, APE1/ref-1 may inhibit VCAM-1 expression by inhibiting superoxide production and p38 MAPK activation
Fritz et al., J Immunol 2006 : Induction of VCAM-1 by OSM was diminished by pharmacological inhibitors of PI3K ( LY294002 ) but not inhibitors of ERK1/2 ( PD98059 ) or p38 MAPK ( SB203580 )
Ueno et al., Cardiovasc Toxicol 2006 (Atherosclerosis) : Inhibitors of p38 MAPK , PKC, and NF-kappaB suppressed nicotine stimulated expression of ICAM-1 and VCAM-1
Hosokawa et al., Clin Exp Immunol 2006 (Periodontitis) : However, mitogen activated protein kinase ( MEK ) and c-Jun NH2-terminal kinase (JNK) inhibitor enhanced only VCAM-1 expression on HGF
Lin et al., Cell Signal 2007 : Taken together, these results suggest that in HTSMCs, activation of p42/p44 MAPK , p38, and JNK pathways, at least in part, mediated through NF-kappaB, is essential for LPS induced VCAM-1 gene expression
Tung et al., Cell Signal 2007 : In this study, we identified a requirement for PDGFR, PI3-K/Akt, p38 MAPK , JNK, and NF-kappaB in the regulation of VCAM-1 expression by rat vascular smooth muscle cells ( VSMCs ) in response to viral infection
Ho et al., Immunobiology 2008 (Inflammation...) : Selective inhibitors of p38 MAPK ( SB203580 ), JNK ( SP600125 ) and ERK ( PD98059 ) could suppress TNF-alpha induced CCL2 and ICAM-1 expression, while only p38 MAPK and ERK inhibitors could suppress TNF-alpha induced VCAM-1 expression
Binion et al., Am J Physiol Gastrointest Liver Physiol 2009 : We investigated the effect of curcumin, phosphatidylinositol 3-kinase ( PI 3-kinase ) /protein kinase B ( Akt ), and mitogen activated protein kinase ( MAPK ) inhibitors on VCAM-1 expression and function in HIMEC ... Tumor necrosis factor (TNF)-alpha/lipopolysaccharide (LPS) induced VCAM-1 expression in HIMEC was suppressed by Akt small interfering RNA, curcumin, and inhibitors of NF-kappaB ( SN-50 ), p38 MAPK ( SB-203580 ) and PI 3-kinase/Akt ( LY-294002 ) ... VCAM-1 induction was partially suppressed by p44/42 MAPK ( PD-098059 ) but unaffected by c-Jun NH2-terminal kinase ( SP-600125 ) inhibition
Park et al., J Pharmacol Sci 2009 : Cadmium stimulates the expression of vascular cell adhesion molecule-1 ( VCAM-1 ) via p38 mitogen activated protein kinase ( MAPK ) and JNK activation in cerebrovascular endothelial cells
Azcutia et al., PloS one 2010 (Hyperglycemia...) : Both ERK 1/2 and NF-kappaB were necessary for VCAM-1 expression, but not for ICAM-1 expression
Hsu et al., J Cell Physiol 2011 : Furthermore, resistin increased the expression of intercellular adhesion molecule-1 ( ICAM-1 ) and vascular cell adhesion molecule-1 ( VCAM-1 ) by HUVECs and these effects were also p38MAPK dependent
Liu et al., J Periodontol 2012 (Atherosclerosis...) : In addition, the p38 MAPK inhibitor ( SB 203580 ) significantly attenuated Pg LPS induced VCAM-1 expression ... Activation of p38 MAPK is at least partially involved in Pg LPS induced VCAM-1 expression in HAECs, which may contribute to the acceleration of atherosclerosis
Lee et al., Cell communication and signaling : CCS 2012 : Role of TLR4/NADPH oxidase/ROS activated p38 MAPK in VCAM-1 expression induced by lipopolysaccharide in human renal mesangial cells
Lin et al., PloS one 2012 (Osteoarthritis) : CCL2 mediated VCAM-1 expression was attenuated by CCR2 inhibitor ( RS102895 ), PKCd inhibitor ( rottlerin ), p38MAPK inhibitor ( SB203580 ), and AP-1 inhibitors ( curcumin and tanshinone IIA )
Kawanami et al., Biochem Biophys Res Commun 2013 : These findings indicate that Rho-kinase regulates ER stress mediated VCAM-1 induction by ATF4- and p38MAPK dependent signaling pathways