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FGF4 — GREM1

Text-mined interactions from Literome

Verheyden et al., Nature 2008 : Here we show, by analysing compound mouse mutants defective in genes comprising the positive loop, genetic evidence that FGF signalling can repress Grem1 expression, revealing a novel Fgf/Grem1 inhibitory loop
Mackem et al., Science signaling 2009 : In turn, SHH activity maintains the expression of Gremlin1, which encodes a bone morphogenetic protein ( BMP ) antagonist ; the interaction between BMP and Gremlin1 regulates Fgf gene expression