Gene interactions and pathways from curated databases and text-mining

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KLF6 — PTTG1

Text-mined interactions from Literome

Lee et al., FEBS Lett 2010 (Carcinoma, Hepatocellular...) : In HepG2, KLF6 transcriptionally repressed PTTG1 by direct promoter interaction ... In HepG2, KLF6 transcriptionally repressed PTTG1 by direct promoter interaction
Chen et al., PloS one 2013 : We found that KLF6 could directly bind and repress PTTG1 expression ... Our findings suggest that drugs that increase the KLF6 inhibition of PTTG1 may have a therapeutic application in AML treatment strategies