◀ Back to BMP1

BMP1 — SMURF1

Text-mined interactions from Literome

Murakami et al., Mol Biol Cell 2003 : Herein, we examined whether Smurf1 negatively regulates BMP signaling together with the I-Smads Smad6/7 ... Smurf1 thus controls BMP signaling with and without I-Smads through multiple mechanisms
Zhao et al., J Biol Chem 2004 : To determine the role of Smurf1 in osteoblast differentiation, in the present studies we transfected a Smurf1 expression plasmid into 2T3 osteoblast precursor cells and found that Smurf1 overexpression inhibits BMP signaling and osteoblast differentiation
Yamashita et al., Cell 2005 : However, loss of Smurf1 does not affect the canonical Smad mediated intracellular TGFbeta or BMP signaling ; instead, it leads to accumulation of phosphorylated MEKK2 and activation of the downstream JNK signaling cascade
Alexandrova et al., Dev Biol 2006 : Smurf1 was initially implicated in BMP pathway regulation in embryonic development, but its potential role in vertebrate embryogenesis has yet to be clarified
Cui et al., EMBO J 2011 : SCFFBXL15 regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1