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MXD1 — MYC

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: MYC → Complex of MAX-MXD1 (decreases, MAX/MXD1 Activity)
  Evidence: hetero-dimerization of MAX with other HLH-LZ proteins, such as MAD, Mxi-1 and Mnt, which are antagonists of c-MYC-induced transformation

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: MYC — MXD1 (in vivo) Lüscher et al., Gene 2001*
• IRef Hprd Interaction: MYC — MXD1 (in vitro) Lüscher et al., Gene 2001*
• IRef Ophid Interaction: MYC — MXD1 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Menssen et al., Cell cycle (Georgetown, Tex.) 2007 (Chromosomal Instability...) : Here we show that the human BubR1 and MAD2 genes, which encode inhibitors of the anaphase promoting complex (APC/C), are directly activated by the oncogenic transcription factor c-MYC via E-box sequences in their first introns ... Unexpectedly, c-MYC induced CIN was independent of c-MYC induced BubR1/MAD2 expression and mitotic delay
Boult et al., Br J Cancer 2008 (Adenocarcinoma...) : Overexpression of c-MYC and MAD proteins in SEG1 cells resulted in differential expression of MYC/MAX/MAD network members and reciprocal changes in proliferation ... Overexpression of c-MYC and MAD proteins in SEG1 cells resulted in differential expression of MYC/MAX/MAD network members and reciprocal changes in proliferation