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PRKAR1B — SLC9A3R1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Déliot et al., Am J Physiol Cell Physiol 2005
:
Moreover, in mouse kidney slices, PTH induced an increase in NHERF1 phosphorylation ; independent activation of
PKA or PKC also
resulted in increased phosphorylation of
NHERF1 in kidney slices
Guerra et al., J Biol Chem 2005
(Cystic Fibrosis) :
Importantly, wt
NHERF1 overexpression in confluent DeltaF508 CFBE41o- and DeltaF508 CFT1-C2 cell monolayers
induced both a significant redistribution of CFTR from the cytoplasm to the apical membrane and a
PKA dependent activation of CFTR dependent chloride secretion
Monterisi et al., J Cell Sci 2012
:
NHERF1 overexpression in CFBE41o-cells
restores chloride secretion, subcortical cAMP compartmentalization and local
PKA activity, indicating that regulation of dF508CFTR function requires not only stable expression of the mutant CFTR at the cell surface but also depends on both generation of local cAMP signals of adequate amplitude and activation of PKA in proximity of its target
Wang et al., J Biol Chem 2012
:
Activation of ezrin anchored
PKA initiates
NHERF1 phosphorylation to disassemble the ternary complex, release Npt2a, and thereby inhibit phosphate transport
Wang et al., Bone 2013
:
NHERF1 regulation of PTH-sensitive Pi uptake in proliferating osteoblasts is
mediated by
cAMP/PKA and PLC/PKC, while modulation of Pi uptake in differentiated osteoblasts depends only on cAMP/PKA signaling