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PRKAR1B — VIP
Text-mined interactions from Literome
Kishi et al., Br J Pharmacol 2000
:
Thus, the present study suggests that
activation of
PKA via activation of
VIP receptors is associated with activation of ChTx-sensitive K ( + ) channels in relaxation of longitudinal muscle of the distal colon of Wistar-ST rats
Fernández et al., J Mol Endocrinol 2005
:
Studies in GH4C1 cells, with an expression vector for Rap1 GTPase activating protein ( Rap1 GAP1 ), demonstrated reduced VIP induced MAPK activation, indicating that
VIP dependent activation of the extracellular signal regulated kinase ( ERK ) pathway
requires PKA-Rap1 signaling ... IGF-I and
VIP stimulation of CRE mediated transcription
required activation of both Ras-MAPK and
cAMP/PKA signaling