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IL10 — TCF3
Text-mined interactions from Literome
McDermott et al., Trends Mol Med 2002
(Familial Mediterranean Fever...) :
Disorders of
interleukin-1 processing and of
regulation of nuclear factor kappaB
transcription factor , and possibly defective apoptosis, might be involved in the pathogenesis of all but one of these disorders
Tryzmel et al., Pediatr Res 2003
:
We determined whether
IL-10 produces a dose related inhibition of proinflammatory chemokine release from stimulated neutrophils of the newborn and whether the mechanism
involves the pivotal
transcription factor , nuclear factor-kappa B. PMNs isolated from the cord blood of healthy newborns were stimulated submaximally with either lipopolysaccharide ( n = 5 ) or tumor necrosis factor ( n = 4 ), with and without IL-10 ( 0.01-1000 ng/mL )
Wong et al., J Biomed Mater Res A 2004
(Osteolysis) :
Effects of
interleukin-10 on titanium particle
induced macrophage
transcription factor activation and cytokine expression in vitro
Dillon et al., J Immunol 2004
(MAP Kinase Signaling System) :
Thus, Pam-3-cys induces enhanced extracellular signal regulated kinase signaling, compared with LPS, resulting in suppressed IL-12 ( p70 ) and enhanced
IL-10 production, as well as enhanced
induction of the
transcription factor , c-Fos
Stearns et al., Mol Cancer Res 2004
(Prostatic Neoplasms) :
Interleukin-10 induced activating
transcription factor 3 transcriptional suppression of matrix metalloproteinase-2 gene expression in human prostate CPTX-1532 Cells
Rahim et al., Immunology 2005
:
Interleukin-10 (IL-10) mediated suppression of IL-12 production in RAW 264.7 cells also involves c-rel
transcription factor
Radons et al., Int J Mol Med 2006
(Chondrosarcoma) :
Although RT-PCR analyses demonstrated the expression of both receptor chains of the IL-10 receptor complex ( IL-10R1 and IL-10R2 ), exposure of SW1353 to IL-10 did not lead to phosphorylation of STAT3, the major
transcription factor induced by
IL-10
Barton et al., Expert Opin Ther Targets 2006
:
Whether DCs are immune stimulatory or tolerogenic apparently rests with whether or not the DCs express activated signal transducer and activator of transcription-3 ( STAT3 ), the
transcription factor induced by IL-6-like cytokines and
IL-10
Sheikh et al., Hepatology 2008
(Hepatitis C...) :
This
transcription factor plays a key role in the expression of cytokines, tumor necrosis factor alpha (TNF-alpha),
interleukin 6, interleukin 8, tumor growth factor beta, and Fas ligand
Chen et al., Immunity 2008
(Arthritis, Rheumatoid...) :
IRF-4 binding protein
inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4
transcription factor
Saraiva et al., Immunity 2009
:
Interleukin-10 production by Th1 cells requires
interleukin-12 induced STAT4
transcription factor and ERK MAP kinase activation by high antigen dose ...
Interleukin-10 production by Th1 cells
requires interleukin-12 induced STAT4
transcription factor and ERK MAP kinase activation by high antigen dose
Iwasaki et al., Eur J Immunol 2013
:
Egr-2
transcription factor is
required for Blimp-1 mediated
IL-10 production in IL-27 stimulated CD4 ( + ) T cells
Hurme et al., Immunol Lett 1994
:
The data obtained demonstrate that
interleukin-10 alone can
activate the AP-1
transcription factor and potentiate the interleukin-2 induced NF-kappa B activity
Weber-Nordt et al., J Immunol 1994
:
Functional analyses of IL-10R expressing cells revealed that
IL-10 activated a cellular
transcription factor in RAW264.7 cells that bound a DNA probe containing the IFN-gamma response region from the Fc gamma RI gene
Sung et al., J Biol Chem 1993
:
Stimulation of
interleukin-1 gene transcription may be
caused by the stimulation of
transcription factor activities, including those of AP-1, by these protein phosphatase inhibitors