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FGR — PIK3R1

Pathways - manually collected, often from reviews:

• KEGG Chemokine signaling pathway: CSK/FGR/HCK/LYN → PIK3CA/PIK3CB/PIK3CD/PIK3CG/PIK3R1/PIK3R2/PIK3R3/PIK3R5 (protein-protein, activation)
  
• WikiPathways Chemokine signaling pathway: CSK/FGR/HCK/LYN → PIK3CA/PIK3CD/PIK3R1/PIK3R2/PIK3R3/PIK3CG/PIK3R5/PIK3CB (activation)
  

Text-mined interactions from Literome

Fumagalli et al., J Immunol 2007 : An increase in intracellular Ca ( 2+ ) concentration and phosphorylation of Akt/PKB occurred normally in fMLP stimulated hck-/-fgr-/- neutrophils, indicating that activation of both phosphoinositide-specific phospholipase C and PI3K is independent of Hck and Fgr
Ko et al., Immunobiology 2011 : The suppression of Fgr with PP2 and Fgr siRNA inhibited activating phosphorylation of PKCd and PI3K/Akt , but not IL-1 receptor associated kinase (IRAK)1, a well-known MyD88 dependent signaling molecule, and Erk1/2, p38, and JNK