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BMP2 — DSPP

Text-mined interactions from Literome

Iohara et al., J Dent Res 2004 : The expression of dentin sialophosphoprotein (Dspp) and enamelysin/matrix metalloproteinase 20 (MMP20) mRNA confirmed the differentiation of pulp cells into odontoblasts and was stimulated by the morphogenetic signal, bone morphogenetic protein 2 (BMP2)
Iohara et al., Stem Cells 2006 : BMP2 stimulated the expression of dentin sialophosphoprotein (Dspp) and enamelysin in three-dimensional pellet cultures
Lin et al., J Endod 2007 (Dentin, Secondary) : Importantly, BMP-7 expression significantly increased alkaline phosphatase activity and induced the dentin sialophosphoprotein expression in a dose- and time dependent manner, suggesting that BMP-7 promoted the odontoblast differentiation
Chen et al., J Biol Chem 2008 : Bone morphogenetic protein 2 mediates dentin sialophosphoprotein expression and odontoblast differentiation via NF-Y signaling ... We hypothesize that BMP2 regulates DSPP gene transcription and thus odontoblast differentiation ... In contrast, mutations in the NF-Y binding motif reduce BMP2 induced DSPP transcription
Oh et al., J Dent Res 2012 : In tooth germs from post-natal days 3 to 9, BMP-2 and SHP expression increased with DSPP and DMP1 mRNA expression