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CAV1 — NGF
Pathways - manually collected, often from reviews:
-
OpenBEL Selventa BEL large corpus:
CAV1
→
NGF
(increases)
Tan et al., J Biol Chem 2003*
Evidence: Nerve Growth Factor Blocks the Glucose- induced Down-regulation of Caveolin-1 Expression in Schwann Cells via p75 Neurotrophin Receptor Signaling * Wenbin Tan , Shefali Rouen , Kristin M.
Text-mined interactions from Literome
Tan et al., J Biol Chem 2003
(Diabetes Mellitus, Experimental) :
Intriguingly,
nerve growth factor antagonized the enhanced mitogenic response of SCs to neuregulin1-beta1 and
inhibited the glucose induced down-regulation of
Cav-1 transcription, mRNA, and protein expression through p75NTR dependent activation of JNK
Schmitz et al., Cell Mol Neurobiol 2011
:
On the other hand, an over-expression of
caveolin-1 impaired the
NGF stimulated activity of p42/44 mitogen activated protein kinases ( MAPK )