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ADCY9 — GAL

Text-mined interactions from Literome

Amiranoff et al., Eur J Biochem 1991 : The direct inhibitory effect of galanin on the adenylate cyclase activity in Rin14B cell membranes was also demonstrated ( IC50 = 3 nM galanin )
Amiranoff et al., Eur J Biochem 1988 : Overnight treatment of the Rin m 5F cells with pertussis toxin completely abolished the inhibitory effect of galanin on insulin release, cAMP production and adenylate cyclase activity
Habert-Ortoli et al., Proc Natl Acad Sci U S A 1994 : The cloned receptor expressed in COS cells specifically binds human, porcine, and rat galanin with high affinity ( Kd in the nanomolar range ) and mediates the galanin inhibition of adenylate cyclase
Karelson et al., Neuropeptides 1995 : Regulation of adenylate cyclase by galanin , neuropeptide Y, secretin and vasoactive intestinal polypeptide in rat frontal cortex, hippocampus and hypothalamus ... This study characterizes regional regulation of adenylate cyclase by galanin , neuropeptide Y (NPY), secretin and vasoactive intestinal peptide (VIP) in rat brain frontal cortex, hypothalamus and hippocampus ... In our experimental system, galanin caused small detectable activation ( 10-20 % ) of basal adenylate cyclase activity in frontal cortex and hippocampus but had no effect on basal adenylate cyclase activity in hypothalamus