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Ferrero et al., Cancer Res 2008
:
Phosphoinositide 3-kinase/AKT signaling can promote AIB1 stability independently of GSK3 phosphorylation
Lahusen et al., Breast Cancer Res Treat 2009
(Breast Neoplasms) :
However, AIB1 also affects the growth of hormone independent breast cancer and AIB1 levels are limiting for IGF-1-, EGF- and heregulin stimulated biological responses in breast cancer cells and consequently the PI3 K/Akt/mTOR and other EGFR/HER2 signaling pathways are controlled by changes in AIB1 protein levels