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CDH2 — TNF

Text-mined interactions from Literome

Tsutsumimoto et al., J Bone Miner Res 1999 : TNF-alpha ( 10-100 U/ml ) and IL-1beta ( 10-100 ng/ml ) suppressed N-cadherin without changing OB-cadherin expression, while PTH ( 1-100 ng/ml ) had no effect on cadherin expression
Nwariaku et al., Shock 2002 : The purpose of our study was to determine the effect of TNFalpha on VE-cadherin cell-surface expression and to identify the signaling pathways involved in TNF induced changes in cadherin expression
Nwariaku et al., Blood 2004 : We found that tumor necrosis factor (TNF) caused tyrosine phosphorylation of VE-cadherin , separation of lateral cell-cell junctions, and intercellular gap formation in human umbilical vein endothelial cell ( HUVEC ) monolayers
Angelini et al., Am J Physiol Lung Cell Mol Physiol 2006 : PP2 also blocked TNF-alpha induced tyrosine phosphorylation of VE-cadherin , gamma-catenin, and p120(ctn)
Vandooren et al., Arthritis Rheum 2008 (Rheumatic Diseases) : In vitro, cadherin 11 expression by FLS was consistently up-regulated by tumor necrosis factor alpha (TNFalpha) at the protein, but not the messenger RNA, level
Parfiniewicz et al., Acta Pol Pharm 2012 : However, TNF-alpha did not cause such a significant increase in sE-cadherin level