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BMP10 — FGF2
Text-mined interactions from Literome
Ono et al., J Craniofac Surg 1996
:
In this study, we investigated the promotive
effect of
basic fibroblast growth factor (bFGF) on the osteogenetic activity of
bone morphogenetic protein ( BMP ) used in conjunction with porous hydroxyapatite ceramic pellets
Nacamuli et al., Plastic and reconstructive surgery 2005
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Furthermore,
BMP3 is
regulated in calvarial osteoblasts by recombinant human
fibroblast growth factor 2 and by paracrine signaling from dura mater
Xu et al., Cell stem cell 2008
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Using a defined medium, we show here that both TGFbeta and
FGF signals synergize to
inhibit BMP signaling ; sustain expression of pluripotency associated genes such as NANOG, OCT4, and SOX2 ; and promote long-term undifferentiated proliferation of human ESCs
Boswell et al., Dev Biol 2008
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Although
BMP signaling is
required for
FGF to enhance fiber differentiation, the converse is not true
Lee et al., Biochim Biophys Acta 2009
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This process requires, at least in part, the inhibition of
BMP signalling in the ectoderm by noggin, as well as
FGF receptor
activation and Ca2+ signalling
Huang et al., Development 2009
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FGF regulated
BMP signaling is required for eyelid closure and to specify conjunctival epithelial cell fate
Mackem et al., Science signaling 2009
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In turn, SHH activity maintains the expression of Gremlin1, which encodes a bone morphogenetic protein ( BMP ) antagonist ; the interaction between
BMP and Gremlin1
regulates Fgf gene expression
Tirosh-Finkel et al., Development 2010
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BMP mediated inhibition of
FGF signaling promotes cardiomyocyte differentiation of anterior heart field progenitors
Yardley et al., Dev Biol 2012
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Finally, we report that prior to the upregulation of these neural crest markers, the non-neural ectoderm upregulates both
BMP and Wnt molecules in
response to
FGF
Lupo et al., Open biology 2013
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We show that either
BMP inhibition or
activation of
FGF signalling is required for effective neural induction, but these two pathways have distinct outcomes on rostrocaudal patterning