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ALK — IL2

Text-mined interactions from Literome

Zhang et al., Proc Natl Acad Sci U S A 2011 : These results demonstrate that the oncogenic tyrosine kinase NPM-ALK induces epigenetic silencing of the IL-2R? gene and that IL-2R? acts as a tumor suppressor by reciprocally inhibiting expression of NPM-ALK
Takahashi et al., Hokkaido Igaku Zasshi 1986 : Although PHA induced ALK activity from thymocytes of LF but not from thymocytes of HF, crude IL2 induced ALK activity from both fractions ... The ALK activity induced by PHA or IL2 was abrogated by treatment of OKT3 and complement but not by OKT4 or OKT8 and complement ... ALK activity and allospecific cytotoxic killer cell ( allo-CTL ) activity were induced from thymocytes of LF by MLC and from both fractions by MLC with IL2 , but there were some differences between these two activities