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IL8 — PTX4

Text-mined interactions from Literome

Rizzi et al., Eur J Immunol 2004 (HIV Infections) : PTX-B inhibited also interleukin-8 secretion and virus expression stimulated in chronically infected U1 promonocytic cells by intra- and/or extracellular Tat
Schneider et al., Infect Immun 2007 : Stimulation of T cells with holotoxin ( PTx ) or the B subunit alone ( PTxB ) rapidly induces signaling events resulting in inositol phosphate accumulation, Ca ( 2+ ) mobilization, interleukin-2 (IL-2) production, and mitogenic cell growth
Xu et al., Cell Adh Migr 2007 : Interestingly, P-selectin did not induce a detectable interleukine-8 (IL-8) secretion ( < 0.1 ng/ml ) in 30 minutes, whereas a high concentration of IL-8 ( > 50 ng/ml ) was required to increase neutrophil adhesion to Fg. P-selectin induced neutrophil adhesion was significantly inhibited by PP2 ( a Src kinase inhibitor ), but not by pertussis toxin ( PTX ; a GPCR inhibitor )
Szajnik et al., Oncogene 2009 (Carcinoma...) : In MyD88 ( + ) SCOV3 cells, LPS or PTX binding to TLR4 induced IRAK4 activation and cJun phosphorylation, activated the NF-kappaB pathway and promoted interleukin (IL)-8 , IL-6, vascular endothelial growth factor and monocyte chemotactic protein-1 production and resistance to drug induced apoptosis
Qiao et al., Invest Ophthalmol Vis Sci 2012 (MAP Kinase Signaling System) : S1P mediated IL-8 secretion is regulated by PTX , extracellular regulated protein kinases 1/2 ( ERK1/2 ), and p38 mitogen activated protein kinase ( MAPK )
Neuner et al., Immunology 1994 : Due to the therapeutic implications, the present study addressed the in vivo effects of PTX on the release of TNF-alpha, IL-1 beta, IL-6 and IL-8 by human peripheral blood mononuclear cells ( PBMC ) ... Under these conditions, only TNF-alpha was found to be reduced by PTX , while IL-1 beta and IL-8 were not affected, IL-6 was even enhanced
Dong et al., J Clin Immunol 1997 : PTX at a 3.5 x 10 ( -5 ) M concentration significantly inhibited T cell proliferation and the production of tumor necrosis factor-alpha, interleukin-2 , and interleukin-4
D'Hellencourt et al., Int J Immunopharmacol 1996 : We investigated PTX effects on production and mRNA expression of TNF alpha, IL-1 beta, IL-6, IL-8 , TNF beta and IL-10 ... We also noted that the effects of PTX on IL-6, IL-8 and IL-10 production were different in WB and in PBMC culture
Schratzberger et al., Immunopharmacology 1999 : In the present study, we investigated the effects of the anti-inflammatory drug pentoxifylline ( PTX ) on activation of endothelial cells for enhanced adhesion and transmigration of neutrophils by lipopolysaccharide (LPS), tumor necrosis factor-alpha (TNF), interleukin-1 (IL-1) and granulocyte colony stimulating factor ( G-CSF )