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CD40 — TNFSF13B

Text-mined interactions from Literome

Grammer et al., Arthritis Res Ther 2003 (Lupus Erythematosus, Systemic) : Emerging data have demonstrated that B lymphocytes are active participants in humoral immune responses that lead to T-dependent and T-independent differentiation of immunoglobulin secreting plasma cells by homotypic CD154-CD40 interactions as well as continued stimulation by B cell activating factor through B cell maturation antigen, B cell activating factor receptor and transmembrane activater
Lin-Lee et al., J Biol Chem 2006 (Cell Transformation, Neoplastic) : Nuclear fractionation studies revealed the presence of CD40 protein in the nucleoplasm fraction of activated B cells, and chromatin immunoprecipitation assays demonstrated that CD40 binds to and stimulates the BLyS/BAFF promoter, another TNF family member ( TNFSF-13B ) involved in cell survival in the B cell lineage
Zhou et al., Blood 2007 (Lymphoma, B-Cell...) : Wild-type CD40 , but not NLS mutated CD40, further enhances c-Rel mediated Blys promoter activation as well as proliferation in LBCL cells
Zhang et al., Braz J Med Biol Res 2013 : BAFF up-regulated CD40 , CD80, CD86, and IgM expression in B cells