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CASP5 — DST
Text-mined interactions from Literome
Negishi et al., Neurosci Lett 2003
:
In hippocampal neurons, E2 and
BPA significantly
inhibited the staurosporine induced increase in
caspase-3 activity ... In cortical neurons,
BPA and NP significantly
inhibited the increase in
caspase-3 activity, while E2 did not ... Furthermore, low-dose
BPA ( 10 nM ) also significantly
inhibited the increase in
caspase-3 activity in both hippocampal and cortical neurons
Terasaka et al., Anticancer Res 2005
(Carcinoma, Squamous Cell...) :
BPA activated
caspase-9 and caspase-3, suggesting induction of apoptosis via caspase activation by the caspase recruitment domain
Bontempo et al., Journal of translational medicine 2009
(Leukemia, Myeloid, Acute) :
BPA mediated apoptosis was
caspase dependent and occurred by activation of extrinsic and intrinsic cell death pathways modulating both FAS and TRAIL and by inducing BAD phosphorylation in NB4 cells