Gene interactions and pathways from curated databases and text-mining

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IL2 — NR3C2

Text-mined interactions from Literome

Song et al., Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2000 : Adoptive transfer and the effect of IL-2 on MLR were detected to further explore the tolerance mechanism
Shenoy et al., J Clin Immunol 1992 : The suppression of the MLR by suramin is due predominantly to the inhibition of interleukin-2 (IL-2) production by the responding T cells
Yu et al., PloS one 2011 : Proliferation of CD8 ( + ) cells was suppressed by MLR-Tregs in the presence or absence of IL-2
Szawlowski et al., Br J Clin Pharmacol 1985 : Effect of interleukin-2 on the inhibition of the human mixed lymphocyte reaction (MLR) by azathioprine ... Azathioprine ( 36 microM ) inhibited the MLR by 86 % and interleukin-2 ( 25 % ) stimulated the MLR by 99 %
Gondo et al., Cell Immunol 1986 : Experiments on the mixed lymphocyte reaction (MLR) in the presence of exogenous IL-2 showed that lymphocyte proliferation in response to TNP modified cells was higher than that in response to allogeneic cells
Aaron et al., Clin Exp Immunol 1988 : T cell blast stimulation of MLR : role of interleukin 1 and interleukin 2 ... T cells blasts were examined for the ability to stimulate primary mixed leucocyte reactions (MLR) in the presence or absence of supplemental interleukin 1 (IL-1) or interleukin 2 (IL-2)
Tadmori et al., Cytokine 1994 : Together these data suggest that the suppression of MLR by IL-10 requires the effective inhibition of both IL-2 and TNF-alpha production to suppress a synergy between these two cytokines
Tan et al., Int Immunol 1996 (Diabetes Mellitus, Type 1) : MLR-IA does not affect IL-2 receptor expression of responding T cells and has no effect on IL-2 dependent proliferation of CTLL-20 T cells
Bluman et al., Blood 1996 : KL 's enhancement of the MLR also requires the binding of IL-2 to its high-affinity IL-2 receptor