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IL8 — MSH6
Text-mined interactions from Literome
Kiss et al., Inflammation 1999
:
SP and CGRP upregulated the IL-8RA mRNA expression in HaCaT cells, but had no influence on their IL-8 production, whereas,
alpha-MSH had no effect on either the
IL-8 or the IL-8RA mRNA expression in HaCaT cells ... In contrast,
alpha-MSH resulted in a time dependent induction of the
IL-8 mRNA expression in dermal fibroblasts
Cui et al., Ophthalmic Res 2005
:
alpha-MSH inhibited IL-1beta or TNF-alpha stimulated
IL-8 and MCP-1 protein levels in the media ...
alpha-MSH inhibited
IL-8 and MCP-1 expression and protein secretion
Manna et al., Eur J Immunol 2006
(Acute Disease...) :
alpha-MSH did not
inhibit IL-8 binding in purified cell membrane or affinity purified CXCR ... IL-8 or anti-CXCR Ab protected against
alpha-MSH mediated inhibition of
IL-8 binding
Fioretti et al., ACS Nano 2010
:
However, in the absence of LPS, PGA-alpha-MSH
induced IL-8 secretion and proliferation of pulp fibroblasts, whereas free
alpha-MSH inhibited this proliferation
Spaccapelo et al., Eur J Pharmacol 2013
(Brain Ischemia...) :
NDP-a-MSH increased hippocampus dentate gyrus ( DG ) expression of Wnt-3A, ß-catenin, Sonic hedgehog (Shh), Zif268,
interleukin-10 (IL-10) and doublecortin ( DCX ), as detected at days 3, 6 and 10 after the ischemic insult
Hartmeyer et al., J Immunol 1997
:
Alpha-MSH ( 10 ( -10 ) -10 ( -8 ) M ) significantly
up-regulated IL-8 release and mRNA expression by HMEC-1