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EGFR — SP3
Text-mined interactions from Literome
Xu et al., Cancer Res 2007
(Brain Neoplasms...) :
Furthermore,
Sp1/Sp3 binding to this site in the promoter is
enhanced by
EGFR activation both in vitro and in vivo
Chadalapaka et al., Mol Cancer Res 2010
(Urinary Bladder Neoplasms) :
EGFR, a putative Sp-regulated gene, was also decreased in cells transfected with a cocktail ( iSp ) containing small inhibitory RNAs for Sp1, Sp3, and Sp4, and RNA interference with individual Sp knockdown indicated that
EGFR expression was primarily
regulated by Sp1 and
Sp3