UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to PIAS2

ESR1 — PIAS2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Biogrid Interaction: ESR1 — PIAS2 (direct interaction, pull down) Kotaja et al., Mol Endocrinol 2000
IRef Ophid Interaction: PIAS2 — ESR1 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Kotaja et al., Mol Endocrinol 2000 : ARIP3 enhances glucocorticoid receptor dependent transcription more efficiently than Miz1 or PIAS1, and all PIAS proteins also activate estrogen receptor- and progesterone receptor dependent transcription but to a dissimilar degree
Li et al., Biol Cell 2012 : Through sumoylation of AIB1, PIAS1 also promoted the stability of AIB1 and attenuated its interaction with estrogen receptor a ( ERa ) , resulting in repression of the transactivation activity of ERa