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HTRA1 — XIAP
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Tillman et al., Cancer Res 2003
(Colonic Neoplasms) :
In RKO, rottlerin
induced the release of cytochrome c,
HtrA2/Omi , Smac/DIABLO, and AIF from the mitochondria, potentiated in combination with TRAIL, with concomitant caspase activation and down-regulation of
XIAP
He et al., Int J Cancer 2012
(Ovarian Neoplasms) :
Ectopic expression of
HtrA1 led to decreased level of
XIAP in OV167 and OV202 ovarian cancer cells, while knockdown of HtrA1 resulted in increased level of XIAP in SKOV3 ovarian cancer cells ... The cleavage of
XIAP induced by
HtrA1 was enhanced by cisplatin treatment