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APC — ID1
Text-mined interactions from Literome
Wang et al., Oncogene 2008
(Chromosomal Instability) :
During late mitosis,
Id-1 binds to Cdh1 and disrupts the interaction between Cdh1 and APC,
resulting in suppression of
APC ( Cdh1 ) activity ... The negative
effect of
Id-1 on
APC ( Cdh1 ) results in suppression of APC ( Cdh1 ) -induced Aurora A and Cdc20 degradation, leading to failure in cytokinesis
Puram et al., Cell cycle (Georgetown, Tex.) 2010
:
In turn,
Cdc20-APC triggers the degradation of the centrosomally localized protein
Id1 and thereby promotes dendrite growth and elaboration