UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	cic-1	H14E04.5	1e-167	chrIII 2,397,836	C. elegans CIC-1 protein; contains similarity to Pfam domain PF00134 Cyclin, N-terminal domain contains similarity to Interpro domains IPR006670 (Cyclin), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR006671 (Cyclin, N-terminal), IPR015429 (Transcription regulator cyclin)
2	F10E9.7	F10E9.7	n/a	chrIII 8,306,002	contains similarity to Interpro domain IPR016193 (Cytidine deaminase-like)
3	R05F9.9	R05F9.9	n/a	chrII 4,900,966
4	C14A4.11	C14A4.11	n/a	chrII 10,606,420	contains similarity to Pfam domain PF06840 Protein of unknown function (DUF1241) contains similarity to Interpro domain IPR009652 (Protein of unknown function DUF1241)
5	rfc-2	F58F6.4	n/a	chrIV 1,350,136	rfc-2 encodes a member of the AAA family that are ATPases associated with DNA replication and has highest similarity to the mouse Replication factor C 40 kDa subunit, and affects embryonic viability, fertility, and locomotion in a large-scale RNAi screen.
6	ceh-5	C16C2.1	n/a	chrI 9,727,604	ceh-5 encodes a homeodomain protein, similar to the human VENTRAL ANTERIOR HOMEO BOX 2 gene (VAX2; OMIM:604295); CEH-5 is dispensable for viability and gross morphology.
7	K09A11.1	K09A11.1	n/a	chrX 13,263,425	contains similarity to Pfam domains PF05699 (hAT family dimerisation domain) , PF02892 (BED zinc finger) contains similarity to Interpro domains IPR008906 (HAT dimerisation), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
8	lem-2	W01G7.5	n/a	chrII 14,064,559	C. elegans LEM-2 protein; contains similarity to Pfam domain PF03020 LEM domain contains similarity to Interpro domains IPR013142 (LEM-like region), IPR003887 (Lamino-associated polypeptide 2/emerin), IPR011015 (LEM-like fold)
9	csb-1	F53H4.1	n/a	chrX 15,863,557	csb-1 is orthologous to human gene ERCC6 (OMIM:133530, mutated in Cockayne syndrome); CSB-1 is required for embryonic viability, and represses UV-induced apoptosis in germ cells.
10	hcf-1	C46A5.9	n/a	chrIV 7,772,495	C. elegans HCF-1 protein; contains similarity to Pfam domains PF01344 (Kelch motif) (3), PF00041 (Fibronectin type III domain) , PF07646 (Kelch motif) (4)contains similarity to Interpro domains IPR011043 (Galactose oxidase/kelch, beta-propeller), IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III), IPR006652 (Kelch repeat type 1), IPR011498 (Kelch repeat type 2), IPR015915 (Kelch-type beta propeller)
11	F19D8.2	F19D8.2	n/a	chrX 13,835,397	contains similarity to Homo sapiens Splice isoform 1 of Q9UMN6 Myeloid/lymphoid or mixed-lineage leukemia protein 4; ENSEMBL:ENSP00000222270
12	spat-1	F57C2.6	n/a	chrII 14,531,337	spat-1 encodes a divergent ortholog of Drosophila melanogaster AURORA BOREALIS (BORA) and human BORA (OMIM:610510); SPAT-1 is specifically required for PAR protein-dependent cell-polarity; RNAi of spat-1 weakly suppresses the embryonic lethality of par-2(it5ts) at restrictive temperature.
13	fbxb-78	E04A4.1	n/a	chrIV 4,738,137	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
14	T02G6.6	T02G6.6	n/a	chrI 11,821,054	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
15	T08A9.6	T08A9.6	n/a	chrX 7,312,318	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
16	C17H11.5	C17H11.5	n/a	chrX 8,183,262
17	gad-1	T05H4.14	n/a	chrV 6,432,396	The gad-1 gene encodes a WD repeat-containing protein that is required maternally for gastrulation initiation during early embryogenesis by regulating the division timing, spindle orientation, and subsequent inward migration of the two gut precusor (E) cells at the 26-cell stage.
18	str-134	C05E4.6	n/a	chrV 744,563	C. elegans STR-134 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
19	dhs-19	T11F9.11	n/a	chrV 11,489,664	dhs-19 encodes a short-chain dehydrogenase predicted to be mitochondrial.
20	T12E12.3	T12E12.3	n/a	chrIV 5,543,170
21	F37B4.10	F37B4.10	n/a	chrV 2,876,718	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
22	C14F11.2	C14F11.2	n/a	chrX 6,211,298	contains similarity to Pfam domains PF00560 (Leucine Rich Repeat) (6), PF00307 (Calponin homology (CH) domain) contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype), IPR016146 (Calponin-homology), IPR001715 (Calponin-like actin-binding), IPR003590 (Leucine-rich repeat, ribonuclease inhibitor subtype)
23	Y106G6H.15	Y106G6H.15	n/a	chrI 10,473,965	contains similarity to Pfam domain PF07160 Protein of unknown function (DUF1395) contains similarity to Interpro domain IPR009829 (Protein of unknown function DUF1395)
24	nud-2	R11A5.2	n/a	chrI 7,858,613	nud-2 encodes an ortholog of human NDE1 (OMIM:609449) and NDEL1 (OMIM:607538), effectors of LIS1 (OMIM:601545); NUD-2, along with other orthologs of LIS1-associated proteins (NUD-1, DHC-1, CDK-5, and CDKA-1), is required to prevent convulsions induced by exposure to the GABA antagonist pentylenetetrazole (PTZ); nud-2(RNAi), like RNAi of nud-1 et al., not only induces PTZ susceptibility but also causes GABA-containing synaptic vesicles in the ventral nerve cord to be distributed raggedly, and nud-2(RNAi) animals are abnormally susceptible to paralysis by the GABA agonist muscimol; nud-2(RNAi) phenotypes are dominantly enhanced by a heterozygous lis-1 allele, and nud-2(RNAi) delays the recovery from PTZ-induced paralysis of lis-1 heterozygotes.
25	lips-3	F10F2.3	n/a	chrIII 4,617,677	C. elegans LIPS-3 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
26	T24H10.1	T24H10.1	n/a	chrII 9,099,835	contains similarity to Pfam domains PF07500 (Transcription factor S-II (TFIIS), central domain) , PF08711 (Transcription elongation factor S-II protein N terminal) , PF01096 (Transcription factor S-II (TFIIS)) contains similarity to Interpro domains IPR001222 (Zinc finger, TFIIS-type), IPR003618 (Transcription elongation factor S-II, central region), IPR014754 (Transcription elongation factor, TFIIS, N-terminal, fungal-type), IPR003617 (Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type), IPR014765 (Transcription elongation factor, TFIIS/CRSP70, N-terminal), IPR016492 (Transcription elongation factor, IIS), IPR006289 (Transcription elongation factor, TFIIS), IPR010990 (Transcription elongation factor, TFIIS/elongin A/CRSP70, N-terminal)
27	C36B7.4	C36B7.4	n/a	chrX 7,086,834
28	F26F4.6	F26F4.6	n/a	chrIII 4,892,477	contains similarity to Homo sapiens Similar to Suppressor protein SRP40; VG:OTTHUMP00000170311
29	fbxa-95	F28F8.4	n/a	chrV 15,572,053	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
30	C41D11.4	C41D11.4	n/a	chrI 4,442,876
31	F01G12.1	F01G12.1	n/a	chrX 16,395,930	contains similarity to Pfam domain PF04145 Ctr copper transporter family contains similarity to Interpro domain IPR007274 (Ctr copper transporter)
32	C43H8.2	C43H8.2	n/a	chrI 10,623,645	contains similarity to Pfam domain PF09174 Maf1 regulator contains similarity to Interpro domains IPR017152 (RNA polymerase III transcriptional repressor, MAF1), IPR015257 (Maf1 regulator)
33	Y54G11A.11	Y54G11A.11	n/a	chrII 14,350,230	contains similarity to Pfam domain PF05129 Transcription elongation factor Elf1 like contains similarity to Interpro domain IPR007808 (Protein of unknown function DUF701, zinc-binding putative)
34	kup-1	F10C2.2	n/a	chrV 12,036,541	kup-1 encodes a novel protein that is conserved in C. briggsae, but contains no other known homologs; kup-1 is the upstream gene in an operon with pkc-1, which encodes two protein kinase C isoforms of the nPKC isotype; the polycistronic kup-1/pkc-1 mRNA is detected at low levels in embryos and larvae, but its expression greatly increases in adults; as loss of kup-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of kup-1 in C. elegans development and/or behavior is not yet known.
35	C25G6.1	C25G6.1	n/a	chrX 1,271,143	contains similarity to Pfam domain PF03803 Scramblase contains similarity to Interpro domain IPR005552 (Scramblase)
36	his-63	F22B3.2	n/a	chrIV 11,406,611	his-63 encodes an H3 histone; by homology, HIS-63 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-63 is a replication-dependent histone locus.
37	srx-41	F59B1.7	n/a	chrV 3,635,917	C. elegans SRX-41 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR004827 (Basic-leucine zipper (bZIP) transcription factor), IPR000276 (GPCR, rhodopsin-like)
38	Y17D7B.5	Y17D7B.5	n/a	chrV 18,775,675	contains similarity to Interpro domain IPR006583 (CW)
39	C02B8.2	C02B8.2	n/a	chrX 8,144,673
40	Y57G7A.2	Y57G7A.2	n/a	chrII 1,296,418
41	F56G4.4	F56G4.4	n/a	chrI 11,377,362	contains similarity to Interpro domains IPR003604 (Zinc finger, U1-type), IPR000533 (Tropomyosin), IPR001202 (WW/Rsp5/WWP)
42	B0281.8	B0281.8	n/a	chrII 2,312,169	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR000315 (Zinc finger, B-box), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
43	E04F6.10	E04F6.10	n/a	chrII 7,215,446
44	F47E1.1	F47E1.1	n/a	chrX 9,075,645
45	M199.2	M199.2	n/a	chrIV 15,109,806	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
46	R11A5.3	R11A5.3	n/a	chrI 7,863,191	contains similarity to Mycobacterium tuberculosis DNA-binding protein HU homolog (Histone-like protein) (Hlp) (21-kDaslaminin-2-binding protein).; SW:DBH_MYCTU
47	ZK546.5	ZK546.5	n/a	chrII 4,936,745	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
48	mop-25.2	Y53C12A.4	n/a	chrII 9,702,750	mop-25.2 encodes a Mo25 protein that inhibits DHC-1 in vivo; MOP-25.2 is orthologous to fission yeast Mo25p, budding yeast Hym1p, Aspergillus nidulans HymA, human CAB39, and human CAB39L; MOP-25.2 is paralogous to MOP-25.1 and (more distantly) MOP-25.3; mop-25.2(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that MOP-25.2 negatively regulates dynein; in early embryos, MOP-25.2 is associated with the midbody and spindle poles after cytokinesis; MOP-25.2 shares a redundant function with MOP-25.1 in fertility and embryonic viability; in mass RNAi assays, MOP-25.2 is required for normal locomotion, body coloration, speed, and body size.
49	F53F8.1	F53F8.1	n/a	chrV 20,682,534	The F53F8.1 gene encodes a homolog of human WT1, which when mutated leads to Wilms tumour (OMIM:194070).
50	Y73C8C.3	Y73C8C.3	n/a	chrV 3,116,714	contains similarity to Homo sapiens Isoform 3 of Centromeric protein E; ENSEMBL:ENSP00000369365