UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y18D10A.3	Y18D10A.3	0	chrI 12,812,894	contains similarity to Pfam domain PF03853 YjeF-related protein N-terminus contains similarity to Interpro domain IPR004443 (YjeF-related protein, N-terminal)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	T19D2.3	T19D2.3	n/a	chrX 3,939,726
4	Y57G11C.23	Y57G11C.23	n/a	chrIV 14,858,495	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
5	fbxa-96	H03G16.4	n/a	chrX 15,059,361	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
6	C45G9.8	C45G9.8	n/a	chrIII 5,052,953
7	K02D10.2	K02D10.2	n/a	chrIII 8,770,897
8	R03H10.4	R03H10.4	n/a	chrII 4,168,021	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
9	M04D8.5	M04D8.5	n/a	chrIII 10,032,724	contains similarity to Periplaneta americana Large conductance calcium activated potassium channel pSlo spliceforms1-5A.; TR:Q8I9V1
10	fbxa-30	ZC47.4	n/a	chrIII 1,275,041	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
11	irk-1	R03E9.4	n/a	chrX 6,769,400	C. elegans IRK-1 protein; contains similarity to Pfam domain PF01007 Inward rectifier potassium channel contains similarity to Interpro domains IPR013521 (Potassium channel, inwardly rectifying, Kir, conserved region 2), IPR014756 (Immunoglobulin E-set), IPR013518 (Potassium channel, inwardly rectifying, Kir, cytoplasmic), IPR001838 (Potassium channel, inwardly rectifying, Kir-like)
12	B0207.1	B0207.1	n/a	chrI 5,966,138	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR000387 (Protein-tyrosine phosphatase), IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000005 (Helix-turn-helix, AraC type), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000694 (Proline-rich region), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
13	H12D21.5	H12D21.5	n/a	chrV 14,894,419	contains similarity to Interpro domains IPR001307 (Thiosulfate sulfurtransferase), IPR000463 (Cytosolic fatty-acid binding protein), IPR001763 (Rhodanese-like)
14	F18A12.6	F18A12.6	n/a	chrII 3,401,335	F18A12.6 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; F18A12.6 has no clear orthologs in other organisms.
15	R12H7.4	R12H7.4	n/a	chrX 13,217,956	contains similarity to Homo sapiens similar to zinc-finger helicase; ENSEMBL:ENSP00000304137
16	ins-37	F08G2.6	n/a	chrII 13,835,294	ins-37 encodes an insulin-like peptide.
17	ins-39	F21E9.4	n/a	chrX 1,344,119	ins-39 encodes an insulin-like peptide.
18	F11D5.5	F11D5.5	n/a	chrX 3,302,988	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
19	T08B6.5	T08B6.5	n/a	chrIV 4,890,263	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
20	srz-45	Y6G8.1	n/a	chrV 17,593,282	C. elegans SRZ-45 protein; contains similarity to Interpro domain IPR002229 (Blood group Rhesus C/E and D polypeptide)
21	T02E9.3	T02E9.3	n/a	chrV 11,364,314	T02E9.3 encodes a homolog of human melatonin type 1b receptors, and more generally of mammalian dopamine and serotonin (5-HT) receptors; T02E9.3 is partly required for male tail curling, with T02E9.3(RNAi) animals showing reduced curling in exogenous 5-HT; T02E9.3 is required for full sensitivity to 5-HT, normal brood sizes, and pharyngeal pumping; T02E9.3 is expressed in head and tail neurons.
22	Y41C4A.1	Y41C4A.1	n/a	chrIII 11,648,712	contains similarity to Oryza sativa Putative aspartate kinase.; TR:Q851Z6
23	F26A1.3	F26A1.3	n/a	chrIII 4,827,878	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR017442 (Serine/threonine protein kinase-related)
24	C35A11.2	C35A11.2	n/a	chrV 5,387,617
25	W01B6.4	W01B6.4	n/a	chrIV 10,075,527	contains similarity to Interpro domains IPR008962 (PapD-like), IPR000173 (Glyceraldehyde 3-phosphate dehydrogenase)
26	F36D1.6	F36D1.6	n/a	chrI 11,270,696	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domains IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
27	srh-115	Y61B8A.2	n/a	chrV 17,256,442	C. elegans SRH-115 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
28	T09B4.3	T09B4.3	n/a	chrI 6,177,087
29	T02G6.2	T02G6.2	n/a	chrI 11,801,906	contains similarity to Arabidopsis thaliana Hypothetical protein.; TR:Q9C9Y9
30	skr-20	R12H7.5	n/a	chrX 13,223,155	The skr-20 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-20(RNAi) animals are at least superficially normal.
31	C56A3.3	C56A3.3	n/a	chrV 13,533,300	C56A3.3 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that C56A3.3 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
32	F46B6.10	F46B6.10	n/a	chrV 9,801,717	contains similarity to Homo sapiens Hypothetical protein; TR:Q96QJ8
33	C06C6.7	C06C6.7	n/a	chrV 15,993,879	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
34	K01D12.15	K01D12.15	n/a	chrV 12,386,487	contains similarity to Interpro domains IPR001859 (Ribosomal protein P2), IPR000976 (Wilm's tumour protein)
35	try-6	F48A9.3	n/a	chrI 6,586,594	C. elegans TRY-6 protein; contains similarity to Pfam domains PF00089 (Trypsin) , PF03761 (Domain of unknown function (DUF316)) contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
36	ZK1098.6	ZK1098.6	n/a	chrIII 9,527,820	ZK1098.6 encodes a coiled-coil protein that is individually dispensable for viability and gross morphology in RNAi assays, but is cotranscribed with ZK1098.1 and thus might act in concert with it.
37	F18A12.4	F18A12.4	n/a	chrII 3,405,348	F18A12.4 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; F18A12.4 has no clear orthologs in other organisms.
38	T12B3.4	T12B3.4	n/a	chrIV 7,386,993	contains similarity to Pfam domain PF03637 Mob1/phocein family contains similarity to Interpro domain IPR005301 (Mob1/phocein)
39	F25E5.7	F25E5.7	n/a	chrV 7,440,782	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domains IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
40	srj-8	T28A11.9	n/a	chrV 3,248,476	C. elegans SRJ-8 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	F49F1.6	F49F1.6	n/a	chrIV 4,122,198	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
42	tsp-19	D2092.7	n/a	chrI 6,617,424	C. elegans TSP-19 protein; contains similarity to Interpro domain IPR001991 (Sodium:dicarboxylate symporter)
43	F47G6.2	F47G6.2	n/a	chrI 1,475,611	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
44	K10C9.7	K10C9.7	n/a	chrV 1,066,687
45	T11F1.2	T11F1.2	n/a	chrII 2,957,123	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
46	sre-21	C47A10.4	n/a	chrV 17,771,397	C47A10.4 is orthologous to the human gene ALBINISM, OCULAR, TYPE I (OA1; OMIM:300500), which when mutated leads to Nettleship-Falls type ocular albinism.
47	C07B5.3	C07B5.3	n/a	chrX 9,522,844
48	B0524.3	B0524.3	n/a	chrIII 1,888,918
49	ndx-2	W02G9.1	n/a	chrV 2,664,041	ndx-2 encodes a NUDIX hydrolase; by sequence comparison, NDX-2 is predicted to be orthologous to human NUDT5 which, in vitro, possesses ADP-sugar diphosphatase activity; in C. elegans, loss of ndx-2 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, consistent with the proposed nonessential roles for Nudix proteins in eliminating potentially toxic nucleotide metabolites from cells and modulating levels of metabolic intermediates by shuttling them into alternative biochemical pathways.
50	Y62H9A.13	Y62H9A.13	n/a	chrX 11,918,504	contains similarity to Homo sapiens Hu-Claspin; ENSEMBL:ENSP00000251195