UCSC S. cerevisiae Gene Sorter

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UCSC S. cerevisiae Gene Sorter

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#	Name	SGD ORF	Module	BLASTP E-Value	Genome Position	Description
1	YOR304C-A	YOR304C-A	355	n/a	chrXV 888,635	Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck
2	CYC1	YJR048W	355	n/a	chrX 526,499	Cytochrome c, isoform 1 electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration
3	CPA2	YJR109C	355	n/a	chrX 631,263	Large subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor
4	MET6	YER091C	355	n/a	chrV 341,015	Cobalamin-independent methionine synthase, involved in methionine biosynthesis and regeneration requires a minimum of two glutamates on the methyltetrahydrofolate substrate, similar to bacterial metE homologs
5	CPA1	YOR303W	355	n/a	chrXV 883,516	Small subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor translationally regulated by an attenuator peptide encoded by YOR302W within the CPA1 mRNA 5'-leader
6	CDC6	YJL194W	355	n/a	chrX 70,108	Essential ATP-binding protein required for DNA replication, component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association homologous to S. pombe Cdc18p
7	RPP1B	YDL130W	355	n/a	chrIV 230,216	Ribosomal protein P1 beta, component of the ribosomal stalk, which is involved in interaction of translational elongation factors with ribosome accumulation is regulated by phosphorylation and interaction with the P2 stalk component
8	COQ1	YBR003W	355	n/a	chrII 243,519	Hexaprenyl pyrophosphate synthetase, catalyzes the first step in ubiquinone (coenzyme Q) biosynthesis
9	HOP1	YIL072W	355	n/a	chrIX 227,510	Meiosis-specific DNA binding protein that displays Red1p dependent localization to the unsynapsed axial-lateral elements of the synaptonemal complex required for homologous chromosome synapsis and chiasma formation
10	OLE1	YGL055W	355	n/a	chrVII 399,394	Delta(9) fatty acid desaturase, required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria
11	RNR3	YIL066C	355	n/a	chrIX 239,403	Minor isoform of the large subunit of ribonucleotide-diphosphate reductase the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits
12	HXT2	YMR011W	355	n/a	chrXIII 288,891	High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose
13	RPS24B	YIL069C	355	n/a	chrIX 231,961	Protein component of the small (40S) ribosomal subunit identical to Rps24Ap and has similarity to rat S24 ribosomal protein
14	HXT1	YHR094C	355	n/a	chrVIII 291,769	Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting
15	NHP2	YDL208W	355	7e-59	chrIV 87,747	Nuclear protein related to mammalian high mobility group (HMG) proteins, essential for function of H/ACA-type snoRNPs, which are involved in 18S rRNA processing
16	RPN2	YIL075C	355	n/a	chrIX 219,281	Subunit of the 26S proteasome, substrate of the N-acetyltransferase Nat1p
17	FRE1	YLR214W	355	n/a	chrXII 569,597	Ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to uptake by transporters expression induced by low copper and iron levels
18	UGA4	YDL210W	355	n/a	chrIV 85,127	Permease that serves as a gamma-aminobutyrate (GABA) transport protein involved in the utilization of GABA as a nitrogen source catalyzes the transport of putrescine and delta-aminolevulinic acid (ALA) localized to the vacuolar membrane
19	PHD1	YKL043W	355	n/a	chrXI 357,298	Transcriptional activator that enhances pseudohyphal growth physically interacts with the Tup1-Cyc8 complex and recruits Tup1p to its targets regulates expression of FLO11, an adhesin required for pseudohyphal filament formation similar to StuA, an A. nidulans developmental regulator potential Cdc28p substrate
20	ADE17	YMR120C	355	n/a	chrXIII 508,391	Enzyme of 'de novo' purine biosynthesis containing both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities, isozyme of Ade16p ade16 ade17 mutants require adenine and histidine
21	PHO89	YBR296C	355	n/a	chrII 797,660	Na+/Pi cotransporter, active in early growth phase similar to phosphate transporters of Neurospora crassa transcription regulated by inorganic phosphate concentrations and Pho4p
22	ARN2	YHL047C	355	n/a	chrVIII 9,282	Transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates responsible for uptake of iron bound to the siderophore triacetylfusarinine C
23	SPL2	YHR136C	355	n/a	chrVIII 374,877	Protein with similarity to cyclin-dependent kinase inhibitors downregulates low-affinity phosphate transport during phosphate limitation overproduction suppresses a plc1 null mutation GFP-fusion protein localizes to the cytoplasm
24	SIT1	YEL065W	355	n/a	chrV 28,600	Ferrioxamine B transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates transcription is induced during iron deprivation and diauxic shift potentially phosphorylated by Cdc28p
25	SEC28	YIL076W	355	n/a	chrIX 217,103	Epsilon-COP subunit of the coatomer regulates retrograde Golgi-to-ER protein traffic stabilizes Cop1p, the alpha-COP and the coatomer complex non-essential for cell growth
26	MAM33	YIL070C	355	n/a	chrIX 230,672	Acidic protein of the mitochondrial matrix involved in oxidative phosphorylation related to the human complement receptor gC1q-R
27	TIS11	YLR136C	355	n/a	chrXII 416,229	mRNA-binding protein expressed during iron starvation binds to a sequence element in the 3'-untranslated regions of specific mRNAs to mediate their degradation involved in iron homeostasis
28	LYS20	YDL182W	355	n/a	chrIV 134,080	Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway highly similar to the other isozyme, Lys21p
29	NCE103	YNL036W	355	n/a	chrXIV 560,146	Carbonic anhydrase poorly transcribed under aerobic conditions and at an undetectable level under anaerobic conditions involved in non-classical protein export pathway
30	SHR3	YDL212W	355	n/a	chrIV 78,742	Endoplasmic reticulum packaging chaperone, required for incorporation of amino acid permeases into COPII coated vesicles for transport to the cell surface
31	SPC24	YMR117C	355	n/a	chrXIII 501,570	Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p) involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering
32	PUS9	YDL036C	355	n/a	chrIV 388,207	Mitochondrial tRNA:pseudouridine synthase, catalyzes the formation of pseudouridine at position 32 in mitochondrial tRNAs contains an N-terminal mitochondrial targeting sequence
33	LYS21	YDL131W	355	n/a	chrIV 228,054	Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway highly similar to the other isozyme, Lys20p
34	BSC1	YDL037C	355	n/a	chrIV 385,094	Protein of unconfirmed function, similar to cell surface flocculin Muc1p ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression
35	GLE1	YDL207W	355	n/a	chrIV 89,056	Cytoplasmic nucleoporin required for polyadenylated RNA export not essential for protein import contains a nuclear export signal when bound to inositol hexakisphosphate (IP6), functions as an activator for the ATPase activities of Dbp1p and Dbp5p at the nuclear pore complex during mRNA export
36	TIM22	YDL217C	355	n/a	chrIV 68,294	Essential core component of the mitochondrial TIM22 complex involved in insertion of polytopic proteins into the inner membrane forms the channel through which proteins are imported
37	YDL206W	YDL206W	355	n/a	chrIV 91,320	Putative protein of unknown function YDL206W is not an essential protein