UCSC S. cerevisiae Gene Sorter

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UCSC S. cerevisiae Gene Sorter

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#	Name	SGD ORF	Module	BLASTP E-Value	Genome Position	Description
1	ADH1	YOL086C	373	n/a	chrXV 160,071	Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway
2	ADH2	YMR303C	373	n/a	chrXIII 873,814	Glucose-repressible alcohol dehydrogenase II, catalyzes the conversion of ethanol to acetaldehyde involved in the production of certain carboxylate esters regulated by ADR1
3	TDH2	YJR009C	373	n/a	chrX 454,182	Glyceraldehyde-3-phosphate dehydrogenase, isozyme 2, involved in glycolysis and gluconeogenesis tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate detected in the cytoplasm and cell wall
4	TDH3	YGR192C	373	n/a	chrVII 883,311	Glyceraldehyde-3-phosphate dehydrogenase, isozyme 3, involved in glycolysis and gluconeogenesis tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate detected in the cytoplasm and cell wall
5	TDH1	YJL052W	373	n/a	chrX 338,770	Glyceraldehyde-3-phosphate dehydrogenase, isozyme 1, involved in glycolysis and gluconeogenesis tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate detected in the cytoplasm and cell wall
6	PGK1	YCR012W	373	n/a	chrIII 138,371	3-phosphoglycerate kinase, catalyzes transfer of high-energy phosphoryl groups from the acyl phosphate of 1,3-bisphosphoglycerate to ADP to produce ATP key enzyme in glycolysis and gluconeogenesis
7	ENO1	YGR254W	373	n/a	chrVII 1,001,583	Enolase I, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis expression is repressed in response to glucose
8	ENO2	YHR174W	373	n/a	chrVIII 451,983	Enolase II, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis expression is induced in response to glucose
9	TPI1	YDR050C	373	1e-139	chrIV 556,099	Triose phosphate isomerase, abundant glycolytic enzyme mRNA half-life is regulated by iron availability transcription is controlled by activators Reb1p, Gcr1p, and Rap1p through binding sites in the 5' non-coding region
10	GPM1	YKL152C	373	n/a	chrXI 164,013	Tetrameric phosphoglycerate mutase, mediates the conversion of 3-phosphoglycerate to 2-phosphoglycerate during glycolysis and the reverse reaction during gluconeogenesis
11	PGI1	YBR196C	373	n/a	chrII 613,068	Glycolytic enzyme phosphoglucose isomerase, catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate required for cell cycle progression and completion of the gluconeogenic events of sporulation
12	DPM1	YPR183W	373	n/a	chrXVI 901,156	Dolichol phosphate mannose (Dol-P-Man) synthase of the ER membrane, catalyzes the formation of Dol-P-Man from Dol-P and GDP-Man required for glycosyl phosphatidylinositol membrane anchoring, O mannosylation, and protein glycosylation
13	FBA1	YKL060C	373	n/a	chrXI 326,947	Fructose 1,6-bisphosphate aldolase, required for glycolysis and gluconeogenesis catalyzes conversion of fructose 1,6 bisphosphate to glyceraldehyde-3-P and dihydroxyacetone-P locates to mitochondrial outer surface upon oxidative stress
14	UBC4	YBR082C	373	n/a	chrII 406,898	Ubiquitin-conjugating enzyme (E2), mediates degradation of abnormal or excess proteins, including calmodulin and histone H3 interacts with many SCF ubiquitin protein ligases component of the cellular stress response
15	ABP1	YCR088W	373	n/a	chrIII 265,957	Actin-binding protein of the cortical actin cytoskeleton, important for activation of the Arp2/3 complex that plays a key role actin in cytoskeleton organization
16	APA1	YCL050C	373	n/a	chrIII 38,318	Diadenosine 5',5''-P1,P4-tetraphosphate phosphorylase I (AP4A phosphorylase), involved in catabolism of bis(5'-nucleosidyl) tetraphosphates has similarity to Apa2p
17	TPM1	YNL079C	373	n/a	chrXIV 478,865	Major isoform of tropomyosin binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles acetylated by the NatB complex and acetylated form binds actin most efficiently
18	PDI1	YCL043C	373	n/a	chrIII 49,437	Protein disulfide isomerase multifunctional protein resident in the endoplasmic reticulum lumen, essential for the formation of disulfide bonds in secretory and cell-surface proteins, unscrambles non-native disulfide bonds forms a complex with Mnl1p that has exomannosidase activity, processing unfolded protein-bound Man8GlcNAc2 oligosaccharides to Man7GlcNAc2 which promotes degradation in the unfolded protein response
19	SCJ1	YMR214W	373	n/a	chrXIII 695,916	One of several homologs of bacterial chaperone DnaJ, located in the ER lumen where it cooperates with Kar2p to mediate maturation of proteins
20	YDJ1	YNL064C	373	n/a	chrXIV 506,482	Type I HSP40 co-chaperone involved in regulation of the HSP90 and HSP70 functions involved in protein translocation across membranes member of the DnaJ family
21	ITR1	YDR497C	373	n/a	chrIV 1,444,590	Myo-inositol transporter with strong similarity to the minor myo-inositol transporter Itr2p, member of the sugar transporter superfamily expression is repressed by inositol and choline via Opi1p and derepressed via Ino2p and Ino4p
22	EUG1	YDR518W	373	n/a	chrIV 1,479,384	Protein disulfide isomerase of the endoplasmic reticulum lumen, function overlaps with that of Pdi1p may interact with nascent polypeptides in the ER
23	SSE1	YPL106C	373	n/a	chrXVI 351,234	ATPase that is a component of the heat shock protein Hsp90 chaperone complex binds unfolded proteins member of the heat shock protein 70 (HSP70) family localized to the cytoplasm
24	DOG2	YHR043C	373	n/a	chrVIII 193,175	2-deoxyglucose-6-phosphate phosphatase, member of a family of low molecular weight phosphatases, similar to Dog1p, induced by oxidative and osmotic stress, confers 2-deoxyglucose resistance when overexpressed
25	MMF1	YIL051C	373	n/a	chrIX 258,061	Mitochondrial protein required for transamination of isoleucine but not of valine or leucine may regulate specificity of branched-chain transaminases Bat1p and Bat2p interacts genetically with mitochondrial ribosomal protein genes
26	PRE6	YOL038W	373	n/a	chrXV 255,719	Alpha 4 subunit of the 20S proteasome may replace alpha 3 subunit (Pre9p) under stress conditions to create a more active proteasomal isoform GFP-fusion protein relocates from cytosol to the mitochondrial surface upon oxidative stress
27	GPD2	YOL059W	373	n/a	chrXV 217,787	NAD-dependent glycerol 3-phosphate dehydrogenase, homolog of Gpd1p, expression is controlled by an oxygen-independent signaling pathway required to regulate metabolism under anoxic conditions located in cytosol and mitochondria
28	YRB1	YDR002W	373	n/a	chrIV 453,347	Ran GTPase binding protein involved in nuclear protein import and RNA export, ubiquitin-mediated protein degradation during the cell cycle shuttles between the nucleus and cytoplasm is essential homolog of human RanBP1
29	NIF3	YGL221C	373	n/a	chrVII 81,859	Protein of unknown function, similar to Listeria monocytogenes major sigma factor (rpoD gene product) the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
30	MLC1	YGL106W	373	n/a	chrVII 306,784	Essential light chain for Myo1p, light chain for Myo2p stabilizes Myo2p by binding to the neck region interacts with Myo1p, Iqg1p, and Myo2p to coordinate formation and contraction of the actomyosin ring with targeted membrane deposition
31	CRH1	YGR189C	373	n/a	chrVII 877,430	Chitin transglycosylase that functions in the transfer of chitin to beta(1-6) and beta(1-3) glucans in the cell wall similar and functionally redundant to Utr2 localizes to sites of polarized growth expression induced by cell wall stress
32	MRPL19	YNL185C	373	n/a	chrXIV 292,431	Mitochondrial ribosomal protein of the large subunit
33	YNL035C	YNL035C	373	n/a	chrXIV 569,106	Putative protein of unknown function with similarity to proteins containing WD-40 domains green fluorescent protein (GFP)-fusion protein localizes to the nucleus YNL035C is not an essential gene
34	PIR1	YKL164C	373	n/a	chrXI 142,306	O-glycosylated protein required for cell wall stability attached to the cell wall via beta-1,3-glucan mediates mitochondrial translocation of Apn1p expression regulated by the cell integrity pathway and by Swi5p during the cell cycle
35	CCW12	YLR110C	373	n/a	chrXII 369,897	Cell wall mannoprotein with a role in maintenance of newly synthesized areas of cell wall localizes to periphery of small buds, septum region of larger buds, and shmoo tip
36	YPS3	YLR121C	373	n/a	chrXII 389,507	Aspartic protease, member of the yapsin family of proteases involved in cell wall growth and maintenance attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor