UCSC S. cerevisiae Gene Sorter

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UCSC S. cerevisiae Gene Sorter

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#	Name	SGD ORF	Module	BLASTP E-Value	Genome Position	Description
1	AAC1	YMR056C	637	n/a	chrXIII 387,779	Mitochondrial inner membrane ADP/ATP translocator, exchanges cytosolic ADP for mitochondrially synthesized ATP phosphorylated Aac1p is a minor isoform while Pet9p is the major ADP/ATP translocator
2	STE3	YKL178C	637	n/a	chrXI 113,921	Receptor for a factor pheromone, couples to MAP kinase cascade to mediate pheromone response transcribed in alpha cells and required for mating by alpha cells, ligand bound receptors endocytosed and recycled to the plasma membrane GPCR
3	HVG1	YER039C	637	n/a	chrV 228,830	Protein of unknown function, has homology to Vrg4p
4	YLR161W	YLR161W	637	n/a	chrXII 489,169	Putative protein of unknown function YLR156W, YLR159W, and YLR161W are three identical open reading frames encoded near the ribosomal DNA region of chromosome 12
5	YLR159W	YLR159W	637	n/a	chrXII 485,517	Putative protein of unknown function YLR156W, YLR159W, and YLR161W are three identical open reading frames encoded near the ribosomal DNA region of chromosome 12
6	YLR156W	YLR156W	637	n/a	chrXII 472,285	Putative protein of unknown function exhibits a two-hybrid interaction with Jsn1p in a large-scale analysis
7	POX1	YGL205W	637	n/a	chrVII 109,281	Fatty-acyl coenzyme A oxidase, involved in the fatty acid beta-oxidation pathway localized to the peroxisomal matrix
8	APA2	YDR530C	637	n/a	chrIV 1,497,279	Diadenosine 5',5''-P1,P4-tetraphosphate phosphorylase II (AP4A phosphorylase), involved in catabolism of bis(5'-nucleosidyl) tetraphosphates has similarity to Apa1p
9	GIT1	YCR098C	637	n/a	chrIII 297,827	Plasma membrane permease, mediates uptake of glycerophosphoinositol and glycerophosphocholine as sources of the nutrients inositol and phosphate expression and transport rate are regulated by phosphate and inositol availability
10	MGT1	YDL200C	637	n/a	chrIV 100,784	DNA repair methyltransferase (6-O-methylguanine-DNA methylase) involved in protection against DNA alkylation damage
11	SPS19	YNL202W	637	n/a	chrXIV 260,017	Peroxisomal 2,4-dienoyl-CoA reductase, auxiliary enzyme of fatty acid beta-oxidation homodimeric enzyme required for growth and sporulation on petroselineate medium expression induced during late sporulation and in the presence of oleate
12	YKL162C	YKL162C	637	n/a	chrXI 148,234	Putative protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion
13	YKR106W	YKR106W	637	n/a	chrXI 662,365	Proton:glutathione antiporter localized to the vacuolar and plasma membranes expressed at a very low level almost identical to paralog Gex1p potential role in resistance to oxidative stress and modulation of the PKA pathway
14	YBL029W	YBL029W	637	n/a	chrII 166,699	Non-essential protein of unknown function
15	ECM8	YBR076W	637	n/a	chrII 390,759	Non-essential protein of unknown function
16	ICS2	YBR157C	637	n/a	chrII 553,926	Protein of unknown function null mutation does not confer any obvious defects in growth, spore germination, viability, or carbohydrate utilization
17	YHR159W	YHR159W	637	n/a	chrVIII 418,306	Putative protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm potential Cdc28p substrate null mutant is sensitive to expression of the top1-T722A allele
18	PEX18	YHR160C	637	n/a	chrVIII 419,646	Peroxin required for targeting of peroxisomal matrix proteins containing PTS2 interacts with Pex7p partially redundant with Pex21p
19	SHC1	YER096W	637	n/a	chrV 352,467	Sporulation-specific activator of Chs3p (chitin synthase III), required for the synthesis of the chitosan layer of ascospores has similarity to Skt5p, which activates Chs3p during vegetative growth transcriptionally induced at alkaline pH
20	ATG32	YIL146C	637	n/a	chrIX 74,978	Mitochondrial-anchored transmembrane receptor that interacts with the autophagy adaptor protein, Atg11p, and is essential for mitophagy, the selective vacuolar degradation of mitochondria in response to starvation
21	YIL024C	YIL024C	637	n/a	chrIX 308,886	Putative protein of unknown function non-essential gene expression directly regulated by the metabolic and meiotic transcriptional regulator Ume6p
22	IME4	YGL192W	637	n/a	chrVII 143,147	Probable mRNA N6-adenosine methyltransferase required for entry into meiosis transcribed in diploid cells haploids repress IME4 transcription via production of antisense IME4 transcripts antisense transcription is repressed in diploids
23	THI5	YFL058W	637	n/a	chrVI 13,440	Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP) member of a subtelomeric gene family including THI5, THI11, THI12, and THI13
24	GAT1	YFL021W	637	0	chrVI 96,732	Transcriptional activator of genes involved in nitrogen catabolite repression contains a GATA-1-type zinc finger DNA-binding motif activity and localization regulated by nitrogen limitation and Ure2p
25	CIT3	YPR001W	637	n/a	chrXVI 557,107	Dual specificity mitochondrial citrate and methylcitrate synthase catalyzes the condensation of acetyl-CoA and oxaloacetate to form citrate and that of propionyl-CoA and oxaloacetate to form 2-methylcitrate
26	YJL185C	YJL185C	637	n/a	chrX 82,535	Putative protein of unknown function mRNA is weakly cell cycle regulated, peaking in G2 phase YJL185C is a non-essential gene
27	THI11	YJR156C	637	n/a	chrX 729,085	Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP) member of a subtelomeric gene family including THI5, THI11, THI12, and THI13
28	RIM8	YGL045W	637	n/a	chrVII 414,916	Protein involved in proteolytic activation of Rim101p in response to alkaline pH interacts with ESCRT-1 subunits Stp22p and Vps28p essential for anaerobic growth member of the arrestin-related trafficking adaptor family
29	YGR042W	YGR042W	637	n/a	chrVII 579,883	Putative protein of unknown function involved in maintenance of proper telomere length green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus
30	YGR102C	YGR102C	637	n/a	chrVII 694,859	Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex involved in the formation of Q-tRNAQ transposon insertion mutant is salt sensitive and null mutant has growth defects non-tagged protein is detected in purified mitochondria
31	CLD1	YGR110W	637	n/a	chrVII 714,377	Mitochondrial cardiolipin-specific phospholipase functions upstream of Taz1p to generate monolyso-cardiolipin transcription increases upon genotoxic stress involved in restricting Ty1 transposition has homology to mammalian CGI-58
32	HAL1	YPR005C	637	n/a	chrXVI 566,229	Cytoplasmic protein involved in halotolerance decreases intracellular Na+ (via Ena1p) and increases intracellular K+ by decreasing efflux expression repressed by Ssn6p-Tup1p and Sko1p and induced by NaCl, KCl, and sorbitol through Gcn4p
33	YMR114C	YMR114C	637	n/a	chrXIII 496,896	Protein of unknown function may interact with ribosomes, based on co-purification experiments green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm YMR114C is not an essential gene
34	YMR118C	YMR118C	637	n/a	chrXIII 502,439	Protein of unknown function with similarity to succinate dehydrogenase cytochrome b subunit YMR118C is not an essential gene
35	AIM33	YML087C	637	n/a	chrXIII 94,900	Putative protein of unknown function, highly conserved across species and orthologous to human CYB5R4 null mutant displays reduced frequency of mitochondrial genome loss
36	YMR252C	YMR252C	637	n/a	chrXIII 775,517	Putative protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to mitochondria YMR252C is not an essential gene
37	CRF1	YDR223W	637	n/a	chrIV 912,800	Transcriptional corepressor involved in repression of ribosomal protein (RP) gene transcription via the TOR signaling pathway which promotes accumulation of Crf1p in the nucleus role in repression of RP genes varies by strain
38	BSC2	YDR275W	637	n/a	chrIV 1,012,605	Protein of unknown function, ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression
39	ERF2	YLR246W	637	n/a	chrXII 627,657	Subunit of a palmitoyltransferase, composed of Erf2p and Shr5p, that adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage mutants partially mislocalize Ras2p to the vacuole
40	NDL1	YLR254C	637	n/a	chrXII 644,688	Homolog of nuclear distribution factor NudE, NUDEL interacts with Pac1p and regulates dynein targeting to microtubule plus ends
41	HPA2	YPR193C	637	n/a	chrXVI 923,144	Tetrameric histone acetyltransferase with similarity to Gcn5p, Hat1p, Elp3p, and Hpa3p acetylates histones H3 and H4 in vitro and exhibits autoacetylation activity
42	PIB1	YDR313C	637	n/a	chrIV 1,089,649	RING-type ubiquitin ligase of the endosomal and vacuolar membranes, binds phosphatidylinositol(3)-phosphate contains a FYVE finger domain
43	YDL218W	YDL218W	637	n/a	chrIV 66,969	Putative protein of unknown function YDL218W transcription is regulated by Azf1p and induced by starvation and aerobic conditions expression also induced in cells treated with the mycotoxin patulin
44	THI13	YDL244W	637	n/a	chrIV 16,715	Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP) member of a subtelomeric gene family including THI5, THI11, THI12, and THI13
45	THI20	YOL055C	637	n/a	chrXV 225,247	Multifunctional protein with hydroxymethylpyrimidine phosphate (HMP-P) kinase and thiaminase activities involved in thiamine biosynthesis and degradation in a gene family with THI21 and THI22 HMP-P kinase activity redundant with Thi21p
46	YOR186W	YOR186W	637	n/a	chrXV 683,328	Putative protein of unknown function proper regulation of expression during heat stress is sphingolipid-dependent
47	HSP32	YPL280W	637	n/a	chrXVI 12,243	Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S. cerevisiae Hsp31p, Hsp33p, and Sno4p member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease
48	YLL056C	YLL056C	637	n/a	chrXII 27,857	Putative protein of unknown function, transcription is activated by paralogous transcription factors Yrm1p and Yrr1p and genes involved in pleiotropic drug resistance (PDR) expression is induced in cells treated with the mycotoxin patulin
49	YDR262W	YDR262W	637	n/a	chrIV 993,543	Putative protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the vacuole and is induced in response to the DNA-damaging agent MMS gene expression increases in response to Zymoliase treatment
50	JID1	YPR061C	637	n/a	chrXVI 676,429	Probable Hsp40p co-chaperone, has a DnaJ-like domain and appears to be involved in ER-associated degradation of misfolded proteins containing a tightly folded cytoplasmic domain inhibits replication of Brome mosaic virus in S. cerevisiae