UCSC S. cerevisiae Gene Sorter

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UCSC S. cerevisiae Gene Sorter

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#	Name	SGD ORF	Module	BLASTP E-Value	Genome Position	Description
1	RME1	YGR044C	607	n/a	chrVII 583,441	Zinc finger protein involved in control of meiosis prevents meiosis by repressing IME1 expression and promotes mitosis by activating CLN2 expression directly repressed by a1-alpha2 regulator mediates cell type control of sporulation
2	SOD2	YHR008C	607	n/a	chrVIII 123,239	Mitochondrial manganese superoxide dismutase, protects cells against oxygen toxicity phosphorylated
3	ZWF1	YNL241C	607	n/a	chrXIV 197,184	Glucose-6-phosphate dehydrogenase (G6PD), catalyzes the first step of the pentose phosphate pathway involved in adapting to oxidatve stress homolog of the human G6PD which is deficient in patients with hemolytic anemia
4	YCP4	YCR004C	607	n/a	chrIII 119,946	Protein of unknown function, has sequence and structural similarity to flavodoxins predicted to be palmitoylated the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
5	CMK1	YFR014C	607	n/a	chrVI 173,207	Calmodulin-dependent protein kinase may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to Cmk2p and mammalian Cam Kinase II
6	HMX1	YLR205C	607	0	chrXII 553,200	ER localized heme oxygenase, involved in heme degradation during iron starvation and in the oxidative stress response expression is regulated by AFT1 and oxidative stress relocates to the perinuclear region in the presence of oxidants
7	TMT1	YER175C	607	n/a	chrV 539,913	Trans-aconitate methyltransferase, cytosolic enzyme that catalyzes the methyl esterification of 3-isopropylmalate, an intermediate of the leucine biosynthetic pathway, and trans-aconitate, which inhibits the citric acid cycle
8	GSP2	YOR185C	607	n/a	chrXV 681,775	GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RNA processing and transport interacts with Kap121p, Kap123p and Pdr6p (karyophilin betas) Gsp1p homolog that is not required for viability
9	UPS2	YLR168C	607	n/a	chrXII 499,924	Mitochondrial intermembrane space protein involved in regulation of mitochondrial cardiolipin and phosphatidylethanolamine levels null has defects in mitochondrial morphology similar to Ups1p, Ups3p and to human PRELI
10	YNK1	YKL067W	607	n/a	chrXI 315,042	Nucleoside diphosphate kinase, catalyzes the transfer of gamma phosphates from nucleoside triphosphates, usually ATP, to nucleoside diphosphates by a mechanism that involves formation of an autophosphorylated enzyme intermediate
11	MNN4	YKL201C	607	n/a	chrXI 65,698	Putative positive regulator of mannosylphosphate transferase (Mnn6p), involved in mannosylphosphorylation of N-linked oligosaccharides expression increases in late-logarithmic and stationary growth phases
12	YBR062C	YBR062C	607	n/a	chrII 366,288	Protein of unknown function that interacts with Msb2p may play a role in activation of the filamentous growth pathway.
13	YBR137W	YBR137W	607	n/a	chrII 513,313	Protein of unknown function localized to the cytoplasm binds to Replication Protein A (RPA) also interacts with Sgt2p YBR137W is not an essential gene
14	YHL044W	YHL044W	607	n/a	chrVIII 13,918	Putative integral membrane protein, member of DUP240 gene family green fluorescent protein (GFP)-fusion protein localizes to the plasma membrane in a punctate pattern
15	MUP3	YHL036W	607	n/a	chrVIII 27,061	Low affinity methionine permease, similar to Mup1p
16	DDI1	YER143W	607	n/a	chrV 456,962	DNA damage-inducible v-SNARE binding protein with a role in suppression of protein secretion may play a role in S-phase checkpoint control has ubiquitin-associated (UBA), ubiquitin-like (UBL), and retroviral-like proteinase (RVP) domains
17	YPI1	YFR003C	607	n/a	chrVI 152,890	Inhibitor of the type I protein phosphatase Glc7p, which is involved in regulation of a variety of metabolic processes overproduction causes decreased cellular content of glycogen
18	YJL016W	YJL016W	607	n/a	chrX 406,430	Putative protein of unknown function GFP-fusion protein localizes to the cytoplasm conserved in closely related Saccharomyces species
19	BNA1	YJR025C	607	n/a	chrX 471,404	3-hydroxyanthranilic acid dioxygenase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine expression regulated by Hst1p
20	PTK2	YJR059W	607	n/a	chrX 547,015	Putative serine/threonine protein kinase involved in regulation of ion transport across plasma membrane enhances spermine uptake
21	RTA1	YGR213C	607	n/a	chrVII 918,988	Protein involved in 7-aminocholesterol resistance has seven potential membrane-spanning regions expression is induced under both low-heme and low-oxygen conditions member of the fungal lipid-translocating exporter (LTE) family of protein
22	ALG13	YGL047W	607	n/a	chrVII 411,856	Catalytic component of UDP-GlcNAc transferase, required for the second step of dolichyl-linked oligosaccharide synthesis anchored to the ER membrane via interaction with Alg14p similar to bacterial and human glycosyltransferases
23	YGR111W	YGR111W	607	n/a	chrVII 716,429	Putative protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus
24	YGR130C	YGR130C	607	n/a	chrVII 752,619	Component of the eisosome with unknown function GFP-fusion protein localizes to the cytoplasm specifically phosphorylated in vitro by mammalian diphosphoinositol pentakisphosphate (IP7)
25	YSA1	YBR111C	607	n/a	chrII 461,525	Nudix hydrolase family member with ADP-ribose pyrophosphatase activity shown to metabolize O-acetyl-ADP-ribose to AMP and acetylated ribose 5'-phosphate
26	PET117	YER058W	607	n/a	chrV 271,929	Protein required for assembly of cytochrome c oxidase
27	ADI1	YMR009W	607	n/a	chrXIII 284,371	Acireductone dioxygenease involved in the methionine salvage pathway ortholog of human MTCBP-1 transcribed with YMR010W and regulated post-transcriptionally by RNase III (Rnt1p) cleavage ADI1 mRNA is induced in heat shock conditions
28	YDR248C	YDR248C	607	n/a	chrIV 958,048	Putative protein of unknown function sequence similarity to bacterial and human gluconokinase green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm upregulated by deletion of the RNAP-II associated factor, PAF1
29	MIC14	YDR031W	607	n/a	chrIV 503,680	Mitochondrial intermembrane space protein, required for normal oxygen consumption contains twin cysteine-x9-cysteine motifs
30	YLR257W	YLR257W	607	n/a	chrXII 659,308	Putative protein of unknown function
31	ATG17	YLR423C	607	n/a	chrXII 972,543	Scaffold protein responsible for phagophore assembly site organization regulatory subunit of an autophagy-specific complex that includes Atg1p and Atg13p stimulates Atg1p kinase activity human ortholog RB1CC1/FIP200 interacts with p53, which inhibits autophagy in human cells
32	OPI10	YOL032W	607	n/a	chrXV 265,799	Protein with a possible role in phospholipid biosynthesis, based on inositol-excreting phenotype of the null mutant and its suppression by exogenous choline
33	MCH4	YOL119C	607	n/a	chrXV 95,608	Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane mutant is not deficient in monocarboxylate transport
34	YOR059C	YOR059C	607	n/a	chrXV 439,582	Lipid particle protein of unknown function contains a putative lipase serine active site induced by transcription factor RPN4
35	COX17	YLL009C	607	n/a	chrXII 131,309	Copper metallochaperone that transfers copper to Sco1p and Cox11p for eventual delivery to cytochrome c oxidase contains twin cysteine-x9-cysteine motifs
36	RRI2	YOL117W	607	n/a	chrXV 98,519	Subunit of the COP9 signalosome (CSN) complex that cleaves the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases plays a role in the mating pheromone response