UCSC S. cerevisiae Gene Sorter

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UCSC S. cerevisiae Gene Sorter

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#	Name	SGD ORF	Module	BLASTP E-Value	Genome Position	Description
1	PBI2	YNL015W	565	n/a	chrXIV 605,497	Cytosolic inhibitor of vacuolar proteinase B (PRB1), required for efficient vacuole inheritance with thioredoxin forms protein complex LMA1, which assists in priming SNARE molecules and promotes vacuole fusion
2	INH1	YDL181W	565	n/a	chrIV 135,307	Protein that inhibits ATP hydrolysis by the F1F0-ATP synthase inhibitory function is enhanced by stabilizing proteins Stf1p and Stf2p has similarity to Stf1p has a calmodulin-binding motif and binds calmodulin in vitro
3	OPI3	YJR073C	565	n/a	chrX 572,625	Phospholipid methyltransferase (methylene-fatty-acyl-phospholipid synthase), catalyzes the last two steps in phosphatidylcholine biosynthesis
4	CIT2	YCR005C	565	n/a	chrIII 121,637	Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate, peroxisomal isozyme involved in glyoxylate cycle expression is controlled by Rtg1p and Rtg2p transcription factors
5	INO1	YJL153C	565	n/a	chrX 135,132	Inositol-3-phosphate synthase, involved in synthesis of inositol phosphates and inositol-containing phospholipids transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element
6	GCY1	YOR120W	565	n/a	chrXV 551,583	Putative NADP(+) coupled glycerol dehydrogenase, proposed to be involved in an alternative pathway for glycerol catabolism also has mRNA binding activity member of the aldo-keto reductase (AKR) family
7	TFS1	YLR178C	565	n/a	chrXII 513,491	Protein that interacts with and inhibits carboxypeptidase Y and Ira2p phosphatidylethanolamine-binding protein (PEBP) family member targets to vacuolar membranes during stationary phase acetylated by NatB N-terminal acetyltransferase
8	LAP4	YKL103C	565	n/a	chrXI 246,910	Vacuolar aminopeptidase yscI zinc metalloproteinase that belongs to the peptidase family M18 often used as a marker protein in studies of autophagy and cytosol to vacuole targeting (CVT) pathway
9	STF2	YGR008C	565	n/a	chrVII 508,237	Protein involved in regulation of the mitochondrial F1F0-ATP synthase Stf1p and Stf2p may act as stabilizing factors that enhance inhibitory action of the Inh1p protein
10	SDH2	YLL041C	565	n/a	chrXII 53,531	Iron-sulfur protein subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone as part of the TCA cycle and the mitochondrial respiratory chain
11	GSY1	YFR015C	565	n/a	chrVI 175,328	Glycogen synthase with similarity to Gsy2p, the more highly expressed yeast homolog expression induced by glucose limitation, nitrogen starvation, environmental stress, and entry into stationary phase
12	HSP30	YCR021C	565	0	chrIII 156,608	Hydrophobic plasma membrane localized, stress-responsive protein that negatively regulates the H(+)-ATPase Pma1p induced by heat shock, ethanol treatment, weak organic acid, glucose limitation, and entry into stationary phase
13	GSY2	YLR258W	565	n/a	chrXII 661,774	Glycogen synthase, similar to Gsy1p expression induced by glucose limitation, nitrogen starvation, heat shock, and stationary phase activity regulated by cAMP-dependent, Snf1p and Pho85p kinases as well as by the Gac1p-Glc7p phosphatase
14	GAC1	YOR178C	565	n/a	chrXV 669,050	Regulatory subunit for Glc7p type-1 protein phosphatase (PP1), tethers Glc7p to Gsy2p glycogen synthase, binds Hsf1p heat shock transcription factor, required for induction of some HSF-regulated genes under heat shock
15	TKL2	YBR117C	565	n/a	chrII 475,414	Transketolase, similar to Tkl1p catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway needed for synthesis of aromatic amino acids
16	YRO2	YBR054W	565	2e-37	chrII 343,618	Protein of unknown function with similarity to archaeal rhodopsins the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies transcriptionally regulated by Haa1p
17	RTC2	YBR147W	565	n/a	chrII 537,020	Protein of unknown function mutant produces large lipid droplets, is resistant to fluconazole, has decreased levels of rDNA transcription, growth defects on minimal media, and suppresses cdc13-1 detected in highly purified mitochondria similar to a G-protein coupled receptor from S. pombe
18	TSL1	YML100W	565	n/a	chrXIII 72,272	Large subunit of trehalose 6-phosphate synthase (Tps1p)/phosphatase (Tps2p) complex, which converts uridine-5'-diphosphoglucose and glucose 6-phosphate to trehalose, similar to Tps3p and may share function mutant has aneuploidy tolerance
19	YHR140W	YHR140W	565	n/a	chrVIII 380,931	Putative integral membrane protein of unknown function
20	HXT6	YDR343C	565	n/a	chrIV 1,160,464	High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt7p, expressed at high basal levels relative to other HXTs, repression of expression by high glucose requires SNF3
21	HXT7	YDR342C	565	n/a	chrIV 1,155,072	High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt6p, expressed at high basal levels relative to other HXTs, expression repressed by high glucose levels
22	RGI1	YER067W	565	n/a	chrV 292,308	Protein of unknown function involved in energy metabolism under respiratory conditions protein abundance is increased upon intracellular iron depletion
23	YFR017C	YFR017C	565	n/a	chrVI 182,567	Cytoplasmic protein that inhibits Gdb1p glycogen debranching activity required for normal intracellular accumulation of glycogen phosphorylated in vivo expression increases during wine fermentation
24	DIA3	YDL024C	565	n/a	chrIV 409,154	Protein of unknown function, involved in invasive and pseudohyphal growth
25	NQM1	YGR043C	565	n/a	chrVII 580,935	Transaldolase of unknown function transcription is repressed by Mot1p and induced by alpha-factor and during diauxic shift
26	FMP48	YGR052W	565	n/a	chrVII 594,150	Putative protein of unknown function the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies induced by treatment with 8-methoxypsoralen and UVA irradiation
27	BTN2	YGR142W	565	n/a	chrVII 773,070	v-SNARE binding protein that facilitates specific protein retrieval from a late endosome to the Golgi modulates arginine uptake, possible role in mediating pH homeostasis between the vacuole and plasma membrane H(+)-ATPase
28	FMP43	YGR243W	565	n/a	chrVII 977,556	Putative protein of unknown function expression regulated by osmotic and alkaline stresses the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
29	TPO4	YOR273C	565	n/a	chrXV 835,441	Polyamine transport protein, recognizes spermine, putrescine, and spermidine localizes to the plasma membrane member of the major facilitator superfamily
30	PDH1	YPR002W	565	n/a	chrXVI 559,160	Mitochondrial protein that participates in respiration, induced by diauxic shift homologous to E. coli PrpD, may take part in the conversion of 2-methylcitrate to 2-methylisocitrate