UCSC Human Gene Sorter

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UCSC Human Gene Sorter

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#

Name

VisiGene

BLASTP
E-Value

Genome Position

Description

n/a

n/a

n/a

chr3 47,546,166

Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (PubMed:29332244). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (PubMed:22854966, PubMed:29332244). Involved in cell migration (By similarity). (from UniProt Q0PNE2)