UCSC S. cerevisiae Gene Sorter

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UCSC S. cerevisiae Gene Sorter

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#	Name	SGD ORF	Module	BLASTP E-Value	Genome Position	Description
1	YAR023C	YAR023C	649	n/a	chrI 179,550	Putative integral membrane protein, member of DUP240 gene family
2	YLR462W	YLR462W	649	n/a	chrXII 1,066,260	Putative protein of unknown function with similarity to helicases YLR462W is within the telomere on the right arm of chromosome XII
3	PAU11	YGL261C	649	8e-51	chrVII 6,471	Putative protein of unknown function and member of the seripauperin multigene family encoded mainly in subtelomeric regions mRNA expression appears to be regulated by SUT1 and UPC2
4	DDI3	YNL335W	649	n/a	chrXIV 11,790	Protein of unknown function expression is induced over 100-fold by DNA damage induction decreased in rad6 and rad18 mutants
5	DDI2	YFL061W	649	n/a	chrVI 9,883	Protein of unknown function expression is induced over 100-fold by DNA damage induction decreased in rad6 and rad18 mutants
6	HAP3	YBL021C	649	n/a	chrII 181,877	Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression contains sequences contributing to both complex assembly and DNA binding
7	SNF6	YHL025W	649	n/a	chrVIII 55,350	Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation functions interdependently in transcriptional activation with Snf2p and Snf5p
8	RDS2	YPL133C	649	n/a	chrXVI 300,558	Transcription factor involved in regulating gluconeogenesis and glyoxylate cycle genes member of the zinc cluster family of proteins confers resistance to ketoconazole
9	SAG1	YJR004C	649	n/a	chrX 443,885	Alpha-agglutinin of alpha-cells, binds to Aga1p during agglutination, N-terminal half is homologous to the immunoglobulin superfamily and contains binding site for a-agglutinin, C-terminal half is highly glycosylated and contains GPI anchor
10	DIT1	YDR403W	649	n/a	chrIV 1,275,407	Sporulation-specific enzyme required for spore wall maturation, involved in the production of a soluble LL-dityrosine-containing precursor of the spore wall transcripts accumulate at the time of prospore enclosure
11	DAL82	YNL314W	649	n/a	chrXIV 44,830	Positive regulator of allophanate inducible genes binds a dodecanucleotide sequence upstream of all genes that are induced by allophanate contains an UISALL DNA-binding, a transcriptional activation, and a coiled-coil domain
12	MEK1	YOR351C	649	n/a	chrXV 995,764	Meiosis-specific serine/threonine protein kinase, functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids
13	BUD5	YCR038C	649	n/a	chrIII 198,585	GTP/GDP exchange factor for Rsr1p (Bud1p) required for both axial and bipolar budding patterns mutants exhibit random budding in all cell types
14	ADH7	YCR105W	649	n/a	chrIII 309,612	NADPH-dependent medium chain alcohol dehydrogenase with broad substrate specificity member of the cinnamyl family of alcohol dehydrogenases may be involved in fusel alcohol synthesis or in aldehyde tolerance
15	SPS22	YCL048W	649	n/a	chrIII 42,860	Protein of unknown function, redundant with Sps2p for the organization of the beta-glucan layer of the spore wall
16	PAU3	YCR104W	649	5e-45	chrIII 307,988	Member of the seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme
17	INO2	YDR123C	649	n/a	chrIV 699,011	Component of the heteromeric Ino2p/Ino4p basic helix-loop-helix transcription activator that binds inositol/choline-responsive elements (ICREs), required for derepression of phospholipid biosynthetic genes in response to inositol depletion
18	PAH1	YMR165C	649	n/a	chrXIII 591,334	Mg2+-dependent phosphatidate (PA) phosphatase, catalyzes the dephosphorylation of PA to yield diacylglycerol, responsible for de novo lipid synthesis and formation of lipid droplets homologous to mammalian lipin 1
19	RAD54	YGL163C	649	n/a	chrVII 195,055	DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis member of the SWI/SNF family
20	REC104	YHR157W	649	n/a	chrVIII 413,181	Protein involved in early stages of meiotic recombination required for meiotic crossing over forms a complex with Rec102p and Spo11p necessary during the initiation of recombination
21	PRP18	YGR006W	649	n/a	chrVII 506,447	Splicing factor involved in the positioning of the 3' splice site during the second catalytic step of splicing, part of snRNP U5, interacts with Slu7p
22	SEF1	YBL066C	649	n/a	chrII 98,392	Putative transcription factor, has homolog in Kluyveromyces lactis
23	VBA5	YKR105C	649	n/a	chrXI 659,590	Putative transporter of the Major Facilitator Superfamily (MFS) proposed role as a basic amino acid permease based on phylogeny
24	PCA1	YBR295W	649	n/a	chrII 794,674	Cadmium transporting P-type ATPase may also have a role in copper and iron homeostasis stabilized by Cd binding, which prevents ubiquitination S288C and other lab strains contain a G970R mutation which eliminates Cd transport function
25	LEU5	YHR002W	649	n/a	chrVIII 109,348	Mitochondrial carrier protein involved in the accumulation of CoA in the mitochondrial matrix homolog of human Graves disease protein does not encode an isozyme of Leu4p, as first hypothesized
26	STP2	YHR006W	649	n/a	chrVIII 118,626	Transcription factor, activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids activates transcription of amino acid permease genes
27	YHL042W	YHL042W	649	n/a	chrVIII 15,893	Putative protein of unknown function member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins
28	YPT35	YHR105W	649	n/a	chrVIII 325,088	Endosomal protein of unknown function that contains a phox (PX) homology domain and binds to both phosphatidylinositol-3-phosphate (PtdIns(3)P) and proteins involved in ER-Golgi or vesicular transport
29	YHR210C	YHR210C	649	n/a	chrVIII 521,224	Putative protein of unknown function non-essential gene highly expressed under anaeorbic conditions sequence similarity to aldose 1-epimerases such as GAL10
30	PAU7	YAR020C	649	0.000000002	chrI 176,939	Member of the seripauperin multigene family, active during alcoholic fermentation, regulated by anaerobiosis, inhibited by oxygen, repressed by heme
31	PES4	YFR023W	649	n/a	chrVI 200,791	Poly(A) binding protein, suppressor of DNA polymerase epsilon mutation, similar to Mip6p
32	HXT13	YEL069C	649	n/a	chrV 22,384	Hexose transporter, induced in the presence of non-fermentable carbon sources, induced by low levels of glucose, repressed by high levels of glucose
33	DSF1	YEL070W	649	n/a	chrV 20,343	Deletion suppressor of mpt5 mutation
34	MIG3	YER028C	649	n/a	chrV 211,284	Probable transcriptional repressor involved in response to toxic agents such as hydroxyurea that inhibit ribonucleotide reductase phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, allowing induction of damage response genes
35	YER184C	YER184C	649	n/a	chrV 557,488	Putative zinc cluster protein deletion confers sensitivity to Calcufluor white, and prevents growth on glycerol or lactate as sole carbon source
36	SPO73	YER046W	649	n/a	chrV 243,395	Meiosis-specific protein of unknown function, required for spore wall formation during sporulation dispensible for both nuclear divisions during meiosis
37	PUG1	YER185W	649	n/a	chrV 559,909	Plasma membrane protein with roles in the uptake of protoprophyrin IX and the efflux of heme expression is induced under both low-heme and low-oxygen conditions member of the fungal lipid-translocating exporter (LTE) family of proteins
38	SLZ1	YNL196C	649	n/a	chrXIV 270,723	Sporulation-specific protein with a leucine zipper motif
39	SOK1	YDR006C	649	n/a	chrIV 459,894	Protein whose overexpression suppresses the growth defect of mutants lacking protein kinase A activity involved in cAMP-mediated signaling localized to the nucleus similar to the mouse testis-specific protein PBS13
40	YIA6	YIL006W	649	n/a	chrIX 344,622	Mitochondrial NAD+ transporter, involved in the transport of NAD+ into the mitochondria (see also YEA6) member of the mitochondrial carrier subfamily disputed role as a pyruvate transporter has putative mouse and human orthologs
41	RPR2	YIR015W	649	n/a	chrIX 382,165	Subunit of nuclear RNase P nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs not shared between RNase MRP and RNase P, in contrast to all other RNase P protein subunits
42	RTS2	YOR077W	649	n/a	chrXV 472,248	Basic zinc-finger protein, similar to human and mouse Kin17 proteins which are chromatin-associated proteins involved in UV response and DNA replication
43	ERR3	YMR323W	649	n/a	chrXIII 920,744	Protein of unknown function, has similarity to enolases
44	YFL040W	YFL040W	649	n/a	chrVI 52,161	Putative transporter, member of the sugar porter family YFL040W is not an essential gene
45	IRC18	YJL037W	649	n/a	chrX 376,999	Putative protein of unknown function expression induced in respiratory-deficient cells and in carbon-limited chemostat cultures similar to adjacent ORF, YJL038C null mutant displays increased levels of spontaneous Rad52p foci
46	HFM1	YGL251C	649	n/a	chrVII 29,778	Meiosis specific DNA helicase involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control catalyzes the unwinding of Holliday junctions has ssDNA and dsDNA stimulated ATPase activity
47	PIP2	YOR363C	649	n/a	chrXV 1,021,717	Autoregulatory oleate-specific transcriptional activator of peroxisome proliferation, contains Zn(2)-Cys(6) cluster domain, forms heterodimer with Oaf1p, binds oleate response elements (OREs), activates beta-oxidation genes
48	YGL230C	YGL230C	649	n/a	chrVII 63,993	Putative protein of unknown function non-essential gene
49	MND1	YGL183C	649	n/a	chrVII 156,914	Protein required for recombination and meiotic nuclear division forms a complex with Hop2p, which is involved in chromosome pairing and repair of meiotic double-strand breaks
50	DMA2	YNL116W	649	n/a	chrXIV 409,125	Protein involved in ubiquitination plays a role in regulating spindle position and orientation functionally redundant with Dma1p orthologous to human RNF8 protein, also has sequence similarity to human Chfr