UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	tin-13	DY3.1	3e-40	chrI 8,759,490	C. elegans TIN-13 protein; contains similarity to Pfam domain PF02953 Tim10/DDP family zinc finger contains similarity to Interpro domain IPR004217 (Zinc finger, Tim10/DDP-type)
2	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
3	ZK795.3	ZK795.3	n/a	chrIV 12,559,996	contains similarity to Pfam domain PF04427 Brix domain contains similarity to Interpro domain IPR007109 (Brix)
4	C45G9.5	C45G9.5	n/a	chrIII 5,049,097
5	C38C10.2	C38C10.2	n/a	chrIII 9,388,833	C38C10.2 is orthologous to the human gene SOLUTE CARRIER FAMILY 17 (ANION/SUGAR TRANSPORTER), MEMBER 5 (SLC17A5; OMIM:604322), which when mutated leads to disease.
6	gex-3	F28D1.10	n/a	chrIV 12,406,527	The gex-3 gene encodes a homolog of NAP1/NCKAP1, a mammalian protein ligand of the small GTPase Rac1, and of Drosophila HEM2/NAP1/KETTE; gex-3 is required for tissue morphogenesis and cell migrations; in gex-3 mutants, cells differentiate properly but fail to become organized.
7	C05D11.9	C05D11.9	n/a	chrIII 6,429,174	C05D11.9 encodes an ortholog of Pop1, a protein subunit shared by the endoribonucleases RNase MRP and RNAse P; RNAse MRP cleaves mitochondrial RNA in mitochondrial DNA synthesis, nucleolar pre-rRNA in ribosome synthesis, and at least one mRNA (CLB2) involved in cell-cycle regulation; RNAse P cleaves tRNA precursors to produce their mature 5' end; C05D11.9 is evolutionarily ubiquitous among eukaryotes.
8	cyp-13A11	F14F7.2	n/a	chrIII 13,022,359	C. elegans CYP-13A11 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
9	R01H10.7	R01H10.7	n/a	chrIII 10,264,464	contains similarity to Interpro domain IPR001849 (Pleckstrin-like)
10	F31D4.8	F31D4.8	n/a	chrV 20,862,996	contains similarity to Streptococcus pneumoniae IS3-Spn1 putative transposase.; TR:Q9KK23
11	aos-1	C08B6.9	n/a	chrV 10,128,881	aos-1 encodes the C. elegans ortholog of Saccharomyces cerevisiae Aos1p and human SUMO-1 activating enzyme E1 N subunit; by homology, AOS-1 is predicted to form, with a catalytic subunit, UBA-2, a heterodimeric enzyme that activates the ubiquitin-like protein SMO-1/SUMO in preparation for its covalent attachment to target proteins to regulate their subcellular localization and/or stability; in C. elegans, AOS-1 is required for embryonic and larval development, as well as for proper Hox gene regulation; uba-2/aos-1(RNAi) animals that survive embryogenesis show ectopic expression of EGL-5 and ectopic anterior sensory ray formation.
12	ddx-23	F01F1.7	n/a	chrIII 5,851,012	C. elegans DDX-23 protein; contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR000629 (RNA helicase, ATP-dependent, DEAD-box, conserved site), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014014 (RNA helicase, DEAD-box type, Q motif), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
13	ZK686.2	ZK686.2	n/a	chrIII 7,764,804	ZK686.2 encodes a DEAD-box helicase; loss of ZK686.2 activity via RNAi indicates that ZK686.2 activity is required for positive regulation of growth rate and larval development.
14	ZK858.7	ZK858.7	n/a	chrI 9,143,169	contains similarity to Pfam domain PF04189 Gcd10p family contains similarity to Interpro domains IPR007316 (Eukaryotic initiation factor 3, gamma subunit), IPR017423 (tRNA (adenine-N(1)-)-methyltransferase, non-catalytic TRM6 subunit)
15	hse-5	B0285.5	n/a	chrIII 4,347,680	hse-5 encodes the C. elegans ortholog of the heparan sulfate modifying enzyme glucuronyl C5-epimerase; by homology, HSE-5 is predicted to function in heparan sulfate biosynthesis by catalyzing the chain-modifying epimerization of glucuronic acid to iduronic acid; during development, hse-5 activity is required for normal body size, locomotion, and nervous system development; an hse-5::gfp transcriptional reporter fusion is expressed beginning at early embryonic stages and continuing through adulthood; expression in embryos is nearly ubiquitous with later expression primarily restricted to the hypodermis and intestine.
16	lap-1	ZK353.6	n/a	chrIII 8,400,522	The lap-1 gene encodes a homolog of the zinc metalloprotease leucine aminopeptidase LAP that is predicted to be mitochondrial.
17	pfd-1	C08F8.1	n/a	chrIV 11,150,492	pfd-1 encodes a putative prefoldin subunit 1, orthologous to human PFDN1 (OMIM:604897), that is required for normal microtubule nucleation and growth, embryonic viability, distal tip cell (DTC) migration, and locomotion; PFD-1 is expressed cytoplasmically in most, if not all, tissues; pfd-1(RNAi) animals have sterile progeny and are uncoordinated, and pfd-1(RNAi) embryos show a reduced microtubule growth rate; pfd-1(gk526) or escaper pfd-1(RNAi) hermaphrodites exhibit detective DTC migration.
18	math-18	C40A11.1	n/a	chrII 2,154,617	C. elegans MATH-18 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
19	mog-5	EEED8.5	n/a	chrII 5,402,615	The mog-5 gene encodes a DEAH helicase orthologous to the Drosophila CG8241, the human HRH1, and the S. cerevisiae PRP22 proteins.
20	nas-27	T23F4.4	n/a	chrII 1,177,703	nas-27 encodes an astacin-like metalloprotease; large-scale expression studies reveal that a nas-27::GFP promoter fusion is expressed in the reproductive system, the vulva, and the hypodermis.
21	W02B12.10	W02B12.10	n/a	chrII 11,472,796	contains similarity to Pfam domain PF02390 Putative methyltransferase contains similarity to Interpro domains IPR004395 (Conserved hypothetical protein CHP00091), IPR003358 (Putative methyltransferase)
22	M03C11.8	M03C11.8	n/a	chrIII 10,432,042	contains similarity to Pfam domains PF00271 (Helicase conserved C-terminal domain) , PF00176 (SNF2 family N-terminal domain) contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR000330 (SNF2-related), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
23	C14A4.3	C14A4.3	n/a	chrII 10,586,058	contains similarity to Pfam domain PF03901 Alg9-like mannosyltransferase family contains similarity to Interpro domain IPR005599 (Alg9-like mannosyltransferase)
24	F59A3.3	F59A3.3	n/a	chrI 5,506,231	contains similarity to Pfam domain PF00467 KOW motif contains similarity to Interpro domains IPR005825 (Ribosomal protein L24/L26, conserved site), IPR008991 (Translation protein SH3-like), IPR005824 (KOW), IPR003256 (Ribosomal protein L24)
25	R05G6.4	R05G6.4	n/a	chrIV 7,513,829	contains similarity to Interpro domains IPR003613 (U box), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR016818 (Nitric oxide synthase-interacting)
26	F55A3.7	F55A3.7	n/a	chrI 10,786,484	contains similarity to Pfam domain PF08644 FACT complex subunit (SPT16/CDC68) contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR013953 (FACT complex subunit Spt16p/Cdc68p)
27	npp-15	C29E4.4	n/a	chrIII 7,930,950	C. elegans NPP-15 protein; contains similarity to Pfam domains PF08801 (Nup133 N terminal like) , PF04044 (Nup133 nucleoporin) contains similarity to Interpro domains IPR014908 (Nup133, N-terminal), IPR015943 (WD40/YVTN repeat-like), IPR007187 (Nucleoporin, Nup133-like, C-terminal)
28	syn-16	ZC155.7	n/a	chrIII 5,208,372	C. elegans SYN-16 protein; contains similarity to Pfam domains PF00804 (Syntaxin) , PF05739 (SNARE domain) contains similarity to Interpro domains IPR010989 (t-SNARE), IPR006011 (Syntaxin, N-terminal), IPR000727 (Target SNARE coiled-coil region)
29	C30B5.4	C30B5.4	n/a	chrII 6,196,350	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
30	cua-1	Y76A2A.2	n/a	chrIII 13,447,397	The cua-1 gene encodes a putative E1-E2 ATPase orthologous to the human gene KIAA1347 (ATP7A; OMIM:604384), which when mutated leads to Hailey-Hailey disease.
31	cyn-7	Y75B12B.2	n/a	chrV 15,186,997	cyn-7 encodes a cyclophilin A isoform; while not tested for peptidyl-prolyl isomerase activity in vitro, it is very similar to CYN-3 and closely resembles the prototypical CypA, and is therefore likely to be a member of the cytosolic CsA-binding cyclophilin subfamily; CYN-7 was required for embryonic viability in one set of mass RNAi assays.
32	F10E9.4	F10E9.4	n/a	chrIII 8,309,032	contains similarity to Homo sapiens 14 kDa protein; VG:OTTHUMP00000024648
33	C34B2.8	C34B2.8	n/a	chrI 10,686,429	contains similarity to Pfam domain PF06212 GRIM-19 protein contains similarity to Interpro domain IPR009346 (GRIM-19)
34	srbc-67	T24A6.10	n/a	chrV 3,539,627	C. elegans SRBC-67 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
35	K07F5.14	K07F5.14	n/a	chrIV 9,863,121	contains similarity to Danio rerio Novel protein.; TR:Q1LV47
36	T12E12.2	T12E12.2	n/a	chrIV 5,546,641	contains similarity to Pfam domain PF00385 'chromo' (CHRromatin Organisation MOdifier) domain contains similarity to Interpro domains IPR000953 (Chromo domain), IPR016197 (Chromo domain-like)
37	K09F6.3	K09F6.3	n/a	chrII 2,258,704	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00102 (Protein-tyrosine phosphatase) contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR003125 (Protein of unknown function WSN)
38	T08A11.1	T08A11.1	n/a	chrIII 4,255,571	contains similarity to Interpro domains IPR015425 (Actin-binding FH2), IPR000694 (Proline-rich region), IPR000591 (Pleckstrin/ G-protein, interacting region)
39	drs-2	F10C2.6	n/a	chrV 12,050,440	drs-2 encodes a putative aspartyl-tRNA synthetase.
40	C03H5.3	C03H5.3	n/a	chrII 387,056	contains similarity to Interpro domain IPR002408 (Natriuretic peptide, brain type)
41	dog-1	F33H2.1	n/a	chrI 15,020,116	dog-1 encodes a predicted DEAH helicase, orthologous to the human BRCA1-binding protein BACH1 (OMIM:605882, mutated in early-onset breast cancer); DOG-1 is required for maintenance of polyguanine tracts of germline and somatic DNA, and is proposed to resolve the secondary structure that can occur in guanine-rich DNA during lagging-strand DNA synthesis.
42	K02B2.1	K02B2.1	n/a	chrIV 5,942,943	contains similarity to Pfam domains PF01591 (6-phosphofructo-2-kinase) , PF00300 (Phosphoglycerate mutase family) contains similarity to Interpro domains IPR016260 (Bifunctional 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphate 2-phosphatase), IPR001345 (Phosphoglycerate/bisphosphoglycerate mutase), IPR003094 (Fructose-2,6-bisphosphatase), IPR013079 (6-phosphofructo-2-kinase), IPR013078 (Phosphoglycerate mutase)
43	B0035.11	B0035.11	n/a	chrIV 11,328,468	contains similarity to Pfam domain PF04004 Leo1-like protein contains similarity to Interpro domain IPR007149 (Leo1-like protein)
44	R08D7.1	R08D7.1	n/a	chrIII 8,966,795	contains similarity to Drosophila pseudoobscura GA12417-PA (Fragment).; TR:Q293H8
45	K10B2.4	K10B2.4	n/a	chrII 6,360,595	contains similarity to Pfam domain PF03669 Uncharacterised protein family (UPF0139) contains similarity to Interpro domain IPR005351 (Protein of unknown function UPF0139)
46	F17A9.2	F17A9.2	n/a	chrV 6,111,285	contains similarity to Pfam domains PF04676 (Protein similar to CwfJ C-terminus 2) , PF04677 (Protein similar to CwfJ C-terminus 1) contains similarity to Interpro domains IPR006768 (Protein similar to CwfJ, C-terminal 1), IPR006767 (Protein similar to CwfJ, C-terminal 2), IPR011146 (Histidine triad-like motif)
47	F55H12.2	F55H12.2	n/a	chrI 8,868,112	contains similarity to Interpro domain IPR000242 (Tyrosine specific protein phosphatase)
48	T04A8.6	T04A8.6	n/a	chrIII 4,692,695	T04A8.6 encodes an ortholog of S. cerevisiae NOP15 that may suppress tumorous growth in the germline; like PRO-1, -2, and -3, T04A8.6 is probably required for ribosome biogenesis, suggesting a link between biogenesis in the distal sheath and control of cell division in the germline.
49	Y76G2A.1	Y76G2A.1	n/a	chrI 5,979,820
50	F25G6.8	F25G6.8	n/a	chrV 8,564,846	contains similarity to Pfam domain PF02290 Signal recognition particle 14kD protein contains similarity to Interpro domains IPR009018 (Signal recognition particle, SRP9/SRP14 subunit), IPR003210 (Signal recognition particle, SRP14 subunit)