UCSC S. cerevisiae Gene Sorter

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UCSC S. cerevisiae Gene Sorter

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#	Name	SGD ORF	Module	BLASTP E-Value	Genome Position	Description
1	RAS2	YNL098C	511	n/a	chrXIV 440,086	GTP-binding protein that regulates the nitrogen starvation response, sporulation, and filamentous growth farnesylation and palmitoylation required for activity and localization to plasma membrane homolog of mammalian Ras proto-oncogenes
2	SSC1	YJR045C	511	n/a	chrX 520,620	Hsp70 family ATPase, constituent of the import motor component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex) involved in protein translocation and folding subunit of SceI endonuclease
3	PDA1	YER178W	511	n/a	chrV 547,448	E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex, catalyzes the direct oxidative decarboxylation of pyruvate to acetyl-CoA phosphorylated regulated by glucose
4	CKI1	YLR133W	511	n/a	chrXII 409,319	Choline kinase, catalyzing the first step in phosphatidylcholine synthesis via the CDP-choline (Kennedy pathway) exhibits some ethanolamine kinase activity contributing to phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway
5	SCO1	YBR037C	511	n/a	chrII 311,008	Copper-binding protein of the mitochondrial inner membrane, required for cytochrome c oxidase activity and respiration may function to deliver copper to cytochrome c oxidase has similarity to thioredoxins
6	HSP150	YJL159W	511	n/a	chrX 121,069	O-mannosylated heat shock protein that is secreted and covalently attached to the cell wall via beta-1,3-glucan and disulfide bridges required for cell wall stability induced by heat shock, oxidative stress, and nitrogen limitation
7	YBR284W	YBR284W	511	n/a	chrII 772,435	Putative protein of unknown function YBR284W is not an essential gene null mutant exhibits decreased resistance to rapamycin and wortmannin and synthetic phenotype with alpha-synuclein
8	RCR1	YBR005W	511	n/a	chrII 246,226	Protein of the ER membrane involved in cell wall chitin deposition may function in the endosomal-vacuolar trafficking pathway, helping determine whether plasma membrane proteins are degraded or routed to the plasma membrane
9	ECM29	YHL030W	511	n/a	chrVIII 42,887	Scaffold protein that assists in association of the proteasome core particle with the regulatory particle degraded by the mature proteasome after assembly contains HEAT-like repeats
10	DOG1	YHR044C	511	n/a	chrVIII 194,438	2-deoxyglucose-6-phosphate phosphatase, similar to Dog2p, member of a family of low molecular weight phosphatases confers 2-deoxyglucose resistance when overexpressed, in vivo substrate has not yet been identified
11	GCV3	YAL044C	511	n/a	chrI 58,206	H subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF also required for all protein lipoylation expression is regulated by levels of 5,10-methylene-THF
12	IRC24	YIR036C	511	n/a	chrIX 422,469	Putative benzil reductase (GFP)-fusion protein localizes to the cytoplasm and is induced by the DNA-damaging agent MMS sequence similarity with short-chain dehydrogenase/reductases null mutant has increased spontaneous Rad52p foci
13	OYE3	YPL171C	511	n/a	chrXVI 226,770	Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye2p with different ligand binding and catalytic properties has potential roles in oxidative stress response and programmed cell death
14	ENT3	YJR125C	511	n/a	chrX 655,350	Protein containing an N-terminal epsin-like domain involved in clathrin recruitment and traffic between the Golgi and endosomes associates with the clathrin adaptor Gga2p
15	MSY1	YPL097W	511	n/a	chrXVI 365,691	Mitochondrial tyrosyl-tRNA synthetase
16	CTR1	YPR124W	511	n/a	chrXVI 786,818	High-affinity copper transporter of the plasma membrane, mediates nearly all copper uptake under low copper conditions transcriptionally induced at low copper levels and degraded at high copper levels
17	SLT2	YHR030C	511	n/a	chrVIII 169,617	Serine/threonine MAP kinase involved in regulating maintenance of cell wall integrity, progression through the cell cycle, and nuclear mRNA retention in heat shock required for mitophagy and pexophagy affects recruitment of mitochondria to the phagophore assembly site (PAS) regulated by the PKC1-mediated signaling pathway
18	YAP6	YDR259C	511	n/a	chrIV 975,206	Putative basic leucine zipper (bZIP) transcription factor physically interacts with the Tup1-Cyc8 complex and recruits Tup1p to its targets overexpression increases sodium and lithium tolerance computational analysis suggests a role in regulation of expression of genes involved in carbohydrate metabolism
19	DIC1	YLR348C	511	0.000008	chrXII 827,425	Mitochondrial dicarboxylate carrier, integral membrane protein, catalyzes a dicarboxylate-phosphate exchange across the inner mitochondrial membrane, transports cytoplasmic dicarboxylates into the mitochondrial matrix
20	YDL119C	YDL119C	511	3e-162	chrIV 247,150	Putative mitochondrial transport protein GFP-fusion protein is induced in response to the DNA-damaging agent MMS the authentic, non-tagged protein is detected in purified mitochondria
21	TPO1	YLL028W	511	n/a	chrXII 85,684	Polyamine transporter that recognizes spermine, putrescine, and spermidine catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH phosphorylation enhances activity and sorting to the plasma membrane
22	LAS17	YOR181W	511	n/a	chrXV 676,889	Actin assembly factor, activates the Arp2/3 protein complex that nucleates branched actin filaments localizes with the Arp2/3 complex to actin patches homolog of the human Wiskott-Aldrich syndrome protein (WASP)
23	MPD2	YOL088C	511	n/a	chrXV 154,328	Member of the protein disulfide isomerase (PDI) family, exhibits chaperone activity overexpression suppresses the lethality of a pdi1 deletion but does not complement all Pdi1p functions undergoes oxidation by Ero1p